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Prof. Raed A. Al-Qawasmeh Academic RankProfessor
Raed A. Al-Qawasmeh

Specialization:

  • Organic Chemistry

Contact

- Post Doctoral Researcher, State University of New York at stony Brook, 2000, mentor Prof. Scott Sieburth, Design and synthesis of novel silanediol inhibitors for matrix metalloproteases (MMP). - Ph.D., University of Tübingen (Germany), 1999. Thesis adviser: Prof. Dr. Dr. h.c. Wolfgang Voelter. Thesis title: Anhydropentoses as “Chirons“ for Regio- and Stereoselective Annulation of Aza-, Oxa, and Thiacyclic Systems on Carbohydrate Scaffolds and Novel Neutral Proteinase Inhibitors. - M. Sc. in chemistry, University of Jordan, 1994. Thesis advisor: Prof. Musa Abu Zarga and Prof. Salim Sabri. Thesis title: Chemical Constituents of Flora of Jordan (VII): Constituents of Artemisia arborescens and Alhagi maurorum
01/2019- Professor, Organic chemistry, Department of Chemistry. Sharjah University-sharjah/UAE. 5/14-12/2018 Professor, Organic chemistry, Department of Chemistry. The University of Jordan. 5/10-5/2014 Associate Prof., Organic chemistry, Department of Chemistry. The University of Jordan. 09/05-5/2010 Assistant Prof., Organic chemistry, Department of Chemistry. The University of Jordan. 01/01-12/04 Research Scientist (Project leader): Organic Medicinal Chemistry. Lorus Therapeutics Inc., 2 Meridian Road, Toronto M9W 4Z7 (Now under the Name Aptose Biosciences). 04/99-04/00 Postdoctoral Researcher, Department of Chemistry, State University of New York at Stony Brook. 04/93-04/94 Research assistant at Department of Chemistry /University of Jordan.
- Vice president of the Jordanian Chemical Society. - Member of the department committee for graduate studies. - Member of the department committee for scientific research - Co-Founder of Ghabati: a nonprofit organization aimed to build a green Jordan, to help lower the pollution. The mission is to plant 1000000 trees in selected area to form the core for future public forests. - Member of the committee for organization of scientific lectures for public. - Chair organizing committee for the 1st International Conference on Natural Products and Drug Discovery. - - Member of the organizing committee for the 14th Jordanian Chemical Conference. - Member of the Faculty committee for appointments and promotions. - Faculty representative at the University of Jordan board council. - Member of the department committee for syllabus developments. - Member of the committee of development and accreditation for the Faculty of science. - Member of the scientific committee for the University Model School (The school related to the University with classes from grade one to the highest grade before the university studies). - Department representative at the faculty of science council board. - Member of the faculty of science committee for student behavior and judgments. - Member of the organization committee for the 11th Eurasia conference - Member of the committee for the 10th Jordanian Chemical Society conference.
 “Synthesis and Biological Activity of Nitroimidazole Derivatives Derivatives as Potential Anti-tumor and Anti-bacterial Agents” (135,000 JD)  “Synthesis and Modification of the Bioactive Chiral-Quinolone Scaffolds” This Project was funded from the Deanship of Scientific Research (15,000 JD)  “Synthesis and Bioassay of Some New Dibenzo[b,f][1,4]oxazepine and –thioxazepine Derivatives, Congeners of Loxapine and Quetiapine Antipsychotic Drugs” This Project was funded from the Deanship of Scientific Research (9950 JD)  “Development of a Compliance Monitoring Tool for Diabetes Management based on Hemoglobin A1c” In collaboration with MonoJO a biotechnology company. This project is partially funded from the Higher Councle of Science and technology ( 50,000 JD)  Synthesis and development of some new Tacrine analoge as cholinesterase inhibitors (10,000 JD)  Each master student was finded for his master work with (1500 JD) and the Ph. D (3000 JD)
- SadeekahO W Saber, Raed A Al-Qawasmeh, Luay Abu-Qatouseh, Amneh Shtaiwi, Monther A Khanfar, Yaseen A Al-Soud “Novel hybrid motifs of 4-nitroimidazole-piperazinyl tagged 1,2,3-triazoles: Synthesis, crystal structure, anticancer evaluations, and molecular docking study” Heliyon, 9, 2023, e19327 - Mudassir Jamil, Muhammad Nadeem Akhtar, Muhammad Imran, Ayesha Javaid, Hafiza Komal Zafar, Manzar Sohail, Murad A AlDamen, Magdalena Fitta, Monther A Khanfar, Raed A Al-Qawasmeh “ Photocatalytic degradation of methylene blue dye and electrocatalytic water oxidation over copper (II) complex with mixed ligands” J. Photochem. Photobio. A, 2023, 115095. - Areej Majed Jaber, Mohammed M Al-Mahadeen, Raed A Al-Qawasmeh, Mutasem O. Taha” Synthesis, anticancer evaluation and docking studies of novel adamantanyl-1, 3, 4-oxadiazol hybrid compounds as Aurora-A kinase inhibitors” Medicinal Chemistry Research, 2023 - Gourishetty Srikanth, Anil Ravi, Anusha Sebastian, Jobi Joseph, Monther A Khanfar, Mohammed I El‐Gamal, Raed A Al‐Qawasmeh, Ihsan A Shehadi, Scott McN. Sieburth, Imad A Abu‐Yousef, Amin F Majdalawieh, Taleb H Al‐Tel, “Diastereoselective Synthesis of Camptothecin‐like Scaffolds: Construction of a New Class of Pseudo‐natural Products” Eur. J. Org. Chem. 26 (13), 2023, e202300080. - Anas J Rasras, Raed A Al-Qawasmeh, Mohamed El-Naggar, Ihsan Shehadi, Mahmoud M Elaasser, Yaseen A Al-Soud” Design, synthesis and antimicrobial assessments of aminoacetylenic-piperazine nitroimidazole hybrid compounds” Zeitschrift für Naturforschung C, 78 (3-4), 2023, 113-121. - Gourishetty Srikanth, Anil Ravi, Anusha Sebastian, Jobi Joseph, Monther A Khanfar, Mohammed I El‐Gamal, Raed A Al‐Qawasmeh, Imad A Abu‐Yousef, Amin F Majdalawieh, Taleb H Al‐Tel. “Stereodivergent Transformation of Azepino [3, 4, 5‐cd] indoles En Route to Nature‐Inspired Scaffolds”, Eur. J. org. Chem, 26 (9), 2023, e202201354 - Kamrul Hasan, Reshma G Joseph, Shashikant P Patole, Raed A Al-Qawasmeh, “Development of magnetic Fe3O4-chitosan immobilized Cu (II) Schiff base catalyst: An efficient and reusable catalyst for microwave assisted one-pot synthesis of propargylamines via A3 coupling” Catal. Comm, 174, 2023, 106588 - Anil Ravi, Gourishetty Srikanth, Monther A Khanfar, Raed A Al-Qawasmeh, Mohammed I El-Gamal, Taleb H Al-Tel,” Blue Light-Driven [4+ 2]-Cycloaddition: Diastereoselective Synthesis of Chromeno [4, 3-b] quinoline and Chromeno [4, 3-b][1, 8] naphthyridine Scaffolds” J. Org. Chem. 87 (24), 2022, 16722-16735 63. AJ Rasras, M El-Naggar, NA Safwat, RA Al-Qawasmeh., Cholyl 1, 3, 4-oxadiazole hybrid compounds: design, synthesis and antimicrobial assessment Beilstein Journal of Organic Chemistry 18 (1), 2022, 631-638 - Yaseen A Al-Soud, H Ala’a, Luay Abu-Qatouseh, Amneh Shtaiwi, Alhelal Kafa’AS, Hossam H Al-Suod, Sondos O Alsawakhneh, Raed A Al-Qawasmeh “Nitroimidazoles Part 9. Synthesis, molecular docking, and anticancer evaluations of piperazine-tagged imidazole derivatives” Zeitschrift für Naturforschung B , 2021, 76 (5), 293-302 - Bader A Salameh, Kayed A Abu-Safieh, Eman H Al-Hushki, Wamidh H Talib, Israa A Al- ataby, Raed A Al-Qawasmeh “New maleimide 1,2,3-triazole hybrids: design, synthesis, anticancer, and antimicrobial activities” Monatshefte für Chemie-Chemical Monthly 2020, 151 (10), 1609-1619 - Raed A Al‐Qawasmeh, Nura A Hussein, Ihsan Shehadi, Monther A Khanfar, Bader A Salameh” Design and Synthesis of Aminoacetylenic Indole and Carbazole Hybrid Compounds” ChemistrySelect 2020, 5 (22), 6834-6839 - Raed A. Al-Qawasmeh, Louy A. Al-Nazer, Sarah A. Dawlat-Kari, Luay Abu-Qatouseh, Salim S. Sabri, Murad A. AlDamen and Mutasem Sinnokrot ”Design, Synthesis and Characterization of Novel Isoxazole Tagged Indole Hybrid Compounds” Open Chemistry 2020, 18(1), 138-148. - Raed A. Al-Qawasmeh, Yaseen A. Al-Soud, Kafa’ A. S. Alhelal, Monther A. Khanfar” Crystal structure of 3-(1-benzyl-2-ethyl-4-nitro-1Himidazol-5-ylthio)-propanoic acid, C15H17N3O4S” Z. Kristallogr. NCS, 2020, accepted. -. MA AlDamen, MO Sinnokrot, SB Atta, RA Al Qawasmeh, CJ Gómez-García “Crystal structure and magnetic properties of a new Wells-Dawson [bP 2 CoW 17 O 62] 10-polyoxoanion” J. Struc. Chem. 2020,61,(4), 589-595. - Fatema Hersi, Hany A. Omar, Raed A. Al-Qawasmeh, Zainab Ahmad, Areej M. Jaber, Dana M. Zaher, Taleb H. Al-Tel ”Design and synthesis of new energy restriction mimetic agents: Potent anti-tumor activities of hybrid motifs of aminothiazoles and coumarins” Scientific Reports, 10, 2020, 2393 - Bader A. Salameh, , Haneen Mahmoud and Munther Khanfar Raed A. Al-qawasmeh “Benzimidazole derivatives via Regioselective substitution of dichloro pyrrolobenzimidazole” J. Heterocycl. Chem. 56(5), 2019, 1530-1541 - Anas J. Rasras, Mutasem Sinnokrot, Murad A. AlDamen, Monther A. Khanfar, Raed A. Al-Qawasmeh” The crystal structure of 3-(1H-benzo[d]imidazol-2-yl)-7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydroquinolin-dimethylsulfoxide (1/1),C21H19ClFN3O2S” Z. Kristallogr. NCS, 234(4), 2019, 645-647. - Vunnam Srinivasulu, Paul Schilf, Saleh Ibrahim, Monther A Khanfar, Scott McN Sieburth, Hany Omar, Anusha Sebastian, Raed A AlQawasmeh, Matthew John O’Connor, Taleb H Al-Tel’Multidirectional desymmetrization of pluripotent building block en route to diastereoselective synthesis of complex nature-inspired scaffolds ‘Nature communications, 9(1), 2018, 4989 - Monther A. Khanfar , Areej M. Jaber, Murad A. AlDamen Raed A. Al-Qawasmeh “Synthesis, Characterization, Crystal Structure, and DFT Study of a New Square Planar Cu(II) Complex Containing Bulky Adamantane Ligand” Molecule, 23(3), 2018, 701 46. Hamadeh Tarazi, Raed Abu Odeh, Raed Al-Qawasmeh, Imad Abu Yousef, Wolfgang Voelter, Taleb H Al-Tel “Design, synthesis and SAR analysis of potent BACE1 inhibitors: Possible lead drug candidates for Alzheimer's disease” European Journal of medicinal Chemistry (125), (2017), 1213-1224.. - Al-Qawasmeh R. A.; Huthail B. B.; Sinnokrot M. O.; Semreen M. H.; Odeh R. A; Abu-Zarga M. H.; Tarazi H.; Yousef I. A.; Al-Tel T. H.” Design, Synthesis and Qualitative Structure Activity Relationship Evaluations of Quinoline-Based Bisarylimidazoles as Antibacterial Motifs” Medicinal Chemistry (2016), 12(6), 563-573.
- Al-Qawasmeh, R.; Young, H. A.; Huesca, M.; Lee, Y. "2,4,5-Trisubstituted imidazoles and their use as anti-microbial agents" US 8,394,815 B2 / 2013 - Al-Qawasmeh, R. A.; Zahra, J.; El-Abadelah, M.” Thiadiazolo[3,4-h]quinoline-7-carboxylic acids, salts and esters, processes for their preparation and their use as antiviral, antibiotic and antitumor agents” National Patent Application (2013) Jordan - Huesca, M.; Young, A.; Lee, Y.; Khine, A.; Wright, J.; Lock, L.; AL-Qawasmeh, R. "2-Indolyl imidazo [4,5-D] Phenanthroline derivatives and their use in the treatment of cancer" US 8148392 B2 (2012) - Al-Qawasmeh, R.; Young, H. A.; Huesca, M.; Lee, Y. "2,4,5-Trisubstituted imidazoles and their use as anti-microbial agents" US 7884120 B2/ (2011) - Raed Al-Qawasmeh, “2, 4, 5 - Trisubstituted Imidazoles And Their Use As Anti-Microbial Agents” United States Patent Application, 2007/0105929 - Huesca; Mario, Al-Qawasmeh; Raed, Young; Aiping H, Lee; Yoon” Aryl imidazoles and their use as anti-cancer agents” United States Patent Application, 2007/0123553 - Huesca; M.; Al-Qawasmeh, R.; Young, A. H.; Lee, Y.” Aryl imidazoles and their use as anti-cancer agents” United States Patent Application, 2008/0262015. - Huesca, M.; Young, A.; Lee, Y.; Khine, A.; Wright, J.; Lock, L. Al-Qawasmeh, R. “2-INDOLYL IMIDAZO[4,5-D]PHENANTHROLINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER” WO/2006/126177. - Mario Huesca, Raed A. Al-Qawasmeh, Aiping Young and Yoon Lee “ARYL IMIDAZOLES AND THEIR USE AS ANTI-CANCER AGENTS” WO/2005/047266. - Mario Huesca, Raed A. Al-Qawasmeh, Aiping Young and Yoon Lee “2,4,5-TRISUBSTITUTED IMIDAZOLES AND THEIR USE AS ANTI-MICROBIAL AGENTS” WO/2004/016086.
• DFG scholarship for scientific research visit to Germany. • Grant from from NIH (National Institute of Health) for my research at State University of New York at Stony Brook. • Scholarship from DAAD (Deutscher Akademischer Austausch Dienst, Germany) for Ph. D in organic chemistry at the university of Tübingen, • Grant from DFG (Deutsche Forschung Gemeinshaft) to attend the Polish-German workshop in Stare Jablonki-Poland. • Grant from DFG (Deutsch Forschung Gemeinshaft) to attend the XVIIIth International Carbohydrate Symposium, Milano-Italy. • Scholarship for the young researchers. The Commission of the European Communities. • Grant from ISESCO, Pakistan, for research works at the H. E. J. Research Institute of Chemistry at Karachi, Pakistan. • Scholarship from the University of Jordan. Studying for the M.Sc. • Scholarship from the UNRWA in Jordan. Studying for the B.Sc.
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