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Prof.Ihsan Ali Khlaif Al-Mahasenh Professor Academic Rank• Professor
Ihsan Ali Khlaif Al-Mahasenh

Specialization:

  • Biotechnology & Genetic Engineering

Research Interests:

  • 1. Gene testing & diagnosis of the pathogenic epidemiology in human & microbial systems including the followings: · Sequencing of bacterial & viral genome analysis & phylogenetic analysis · Sequencing human STRs of Y chromosome & phylogenetic analysis · Sequencing human infertility AZF gene cluster, · Gene flow of allelic heterogeneity of Prostate Cancer SNP Mutation of HOX13B-G84E between Europeans & Arabian gene pool 2. Genetic engineering & gene transfer for industrial production of recombinant protein & antibiotics using different expression system of both Eukaryotic & prokaryotic systems

Contact

• Ph.D., Biotechnology & Genetic Engineering, University of Durham, England, U.K. 1988. • M.Sc. Microbiology, Yarmouk University, Jordan. 1984 • B.Sc. Biology, Yarmouk University, Jordan. 1984. • Higher Diploma in Medical Sciences, Medical Institute, Ministry of Health, Jordan. 1977
• Vice-President of Al al-Bayt University& Dean of Scienc College, Dean of Graduate Studies & Research (Mu’tah University) (1988-2011), • Dean of Community Colleges (5 campuses), Dean of College of Medicine, (University of Sharjah 2011-2016), • Professor (1988) & Distinguished Professor (2002). • 2011- Present, Professor of Biotechnology & Genetic Engineering, Department of Biotechnology, University of Sharjah, UAE. • 1994-20011 Professor (1998) and Associate of Biotechnology, Department of Biotechnology, AI al-Bayt University, Jordan (including 4 years 2001-2005 of Sabbatical leave in University of Qatar, Department of Biotechnology & Genetic Engineering. • 1993 Associate Professor, Department of Biological Sciences, Mu'tah University, Jordan. • 1988 Assistant Professor, Department of Biological Sciences, Mu'tah University, Jordan
• Distinctive International Research Contributor to the international Gene/Bank YHRD (Y-STR Haplotype Reference Database), University of Medicine, Berlin, Germany, since 2009. • Distinctive International Research Contributor to the international Gene/Banks of USA (NCBI), DNA Data Bank of Japan (DDBJ), Europe (EMBL), since 2011. • Colleague affiliation & member of Nobel-Prize Holders, New York Academy of Sciences, USA, 1997. • Colleague affiliation & Honorary Appointment to the Research Board of Advisors, American Biographical Institute, USA, 2002. • Honorary Appointment to the Research Board of Advisors, American Biographical Institute, USA, 2002. • Member of the British Society of Cell & Gene Therapy (BSCGT), 2013 • Member of the International Society of Genetic Genealogy (ISOGG), 2013 • Member of the Global Intellectual Society, 2013 • Member, Jordanian Biological Society, 1988 • Member, Arabian Biological Society, 1988 • Honorable Editor for International Journal of Molecular Biology 2016
• Chaired committees: more than 100 committee has been chaired. • Member of committees: more than 100 committee has been membered. • Member & Colleague of Nobel-Prize Holders, New York Academy of Sciences, USA, 1997. • Member (Honorary Appointment) of the Research Board of Advisors, American Biographical Institute, USA, 2002. • Member, Board of Trustees of Zytoona University, Jordan, 1998-2004 • Member, Research Board of Advisors , American Biographical Institute, USA, 2002. • Member, University Council, AL al-Bayt University 1994-2000 • Member, Deans Council, Mu’tah University, 1990-1994 • Member, Deans Council, Al al-Bayt University 1994-2010 • Member, Deans Council, University of Sharjah, 2011-2016 • Member, Governmental Interior Ministry Council of Jerash Province, Jordan, 1997-2000
1. Genetic profiling of the prostate cancer associated with the mutation in the STRs among Arabs 2.Diagnos is of the microdeleation in the AZF-region of the Y chromosome to determine the infertility mutations variants among Arabs males 3.Genetic profiling of the Short Tandem Repeats (STRs) of Y-chromosome of Jordan: towards establishment of gene-therapy platform for the most common genetic diseases 4. Engineering of transgenic bacteria with human insulin expression system capable of insulin production 5. Engineering of transgenic cyanobacteria suitable for bio-signature crust terraforming of the inhospitable Mars environment
1. Ihsan Mahasneh1*, Mustafa Ennaji, Berjas Abumsimir. 2021. Genome Sequences of COVID-19 from Jordanian Patients in Comparison with the Global Pandemic Strains and the Transmission Route . Journal of Biosciences and Medicine, 2021, Vol .9 No 3, 77-93. DOI: 10.4236/jbm.2021.93009. https://www.scirp.org/journal/jbm. 2. Ihsan Ali Mahasneh*, Moulay Mustapha Ennaji, Berjas Abumsimir, Yassine Kasmi. 2021. Presence of G84E Allelic Heterogeneity of the European Prostate Cancer SNP Mutation of HOX13B-G84E Associated with the European R-Haplogroup of Y-Chromosome and Absence of Gene Flow into Moroccans Patients. Journal of Biosciences and Medicine, 2021, Vol. 9 No 5, 50-61. DOI: 10.4236/jbm.2021.95006. https://www.scirp.org/journal/jbm. 3. Mahasneh I.A. and Zuriegat Q.H. 2020/2021. Genetic Profiling of the Short Tandem Repeats (STRs) of Y-Chromosome of Populations of South Jordan. J. Forensic Medicine; 2020/2021, 4(1), 1-16. www.hilarispublisher.com. 4. Mahasneh Ihsan, Ferdos Ebrahim, Ennaji Mustapha, Abumsimir Berjas, 2022. Diagnostic screening of the microdeleation mutations in the AZF-gene cluster of the Y chromosome & prostate cancer among Arabs: Towards establishment of gene therapy platform in the region. Genitourinary cancer: Molecular diagnostic immunological implications: genetic aspect & viral therapy. Elsevier Academic Press 2022. http://store.elsevier.com/Academic 5. Mahasneh, Ihsan, Abumsimir Berjas, Ennaji Mustapha 2022. Global allelic heterogeneity of the HOXB-13 variants of the prostate cancer and the gene therapy in different genealogical lineages of the Y-chromosome haplogroups and STRs microsatellites. In Oncogenic virus: Fundamental and Applications: Volume 1: Fundamental of oncovirues. Volume 2: Medical applications of oncology knowledge. Elsevier academic press, 2022. http://store.elsevier.com/Academic 6. Berjas Abumisimir, Ihsan Mahasneh, Yassin Kasmi, Iman Saif, Rahma Ait Hammou, Moulay Mustafa. Prostate cancer and viral implications: clinical and epidemiological indications. 2022. In Oncogenic virus: Fundamental and Applications: Volume 1: Fundamental of oncovirues. Volume 2: Medical applications of oncology knowledge. Elsevier academic press, 2022. http://store.elsevier.com/Academic 7. Ihsan Mahasneh. 2022. Book Editor-Editorial member of the Book: Genitourinary cancer: Molecular diagnostic immunological implications: genetic aspect & viral therapy. Elsevier Academic Press 2022. http://store.elsevier.com/Academic 8. Ihsan Mahasneh. 2022. Book Editor-Editorial member of the Book: Oncogenic virus: Fundamental and Applications: Volume 1: Fundamental of oncovirues. Volume 2: Medical applications of oncology knowledge. Elsevier academic press, 2022. http://store.elsevier.com/Academic. 9. Molecular evaluation of BK and MC human polyomavirus as promising Prostate cancer markers in Moroccan population. 2022. Moulay Mustapha Ennaji, Ikram TIABI; Berjas ABUMSIMIR; Imane SAIF; Youssef ENNAJI; Soukayna ALAOUI SOSSE; Abdelilah LARAQUI; Ihsan Ali MAHASNEH. Meta Gene. Submitted 12-9-2021. https://doi.org/10.1016/j.mgene.2019.100637. 10. Abumsimir, B., Mrabti, M., Laraqui, A., Ameur, A., Koraishi, S.I., Mzibrie, M., Benchekroun, M.N., Bessi, H., Tiabi, I., Mahasneh, I. and Ennaji, M.M., 2020/2021. Most frequent mutational events of home box 13 gene in prostatic adenocarcinoma and correlation with tumor characteristics. Meta Gene, 23; 1-6. (100637). https://doi.org/10.1016/j.mgene.2019.100637.
• Thesis (48) • Graduation projects (14) • Links for Distinguished Contributions on International Research Platform: in Gene/Bank, International Journals, Books Publishers: 1. Honorable Editor of the International Journal of Molecular Biology (IJMBOA).(http://medcraveonline.com/IJMBOA/editorial-board), 2016 2. Genes Registration in the International DNA Gene Banks of the Nucleotide Sequence Database of GeneBanks of American National Center for Biotechnology Information (NCBI), DNA Data Bank of Japan (DDBJ), European Molecular Biology Laboratory (EMBL) and the. Gene Accession Numbers of AB588124 (www.ncbi.nlm.nih.gov), 2011. 3. Gene Registration in the International Haplotype Reference Database Gene/Bank of the Y-chromosome (YHRD) in the University of Medicine, Berlin, Germany. Gene Accession Numbers of (YA003522) and (YA003523) for The Arabian Genetic Map, 2009. (www.yhrd.org/search), 2009. 4. Human Biology ISBN: 978-994-813-992-5, PP288. University Book Shop, Sharjah, UAE. (www.universitybookshop.ae) , 2016. 5. Man & Environment. ISBN 978-994-818-459-1. PP 333. University Book Shop, Sharjah, UAE. (www.universitybookshop.ae) , 2015.
• Patency in Gene registration in International Gene Banks 1. Mahasneh I. 2011. Genes Registration in the International DNA Gene Banks of the Nucleotide Sequence Database of GeneBanks of American National Center for Biotechnology Information (NCBI), Japan (DDBJ), European Molecular Biology Laboratory (EMBL) and the. Gene Accession Numbers of AB588124 (www.ncbi.nlm.nih.gov). 2. Mahasneh I. 2009. Gene Registration in the International Haplotype Reference Database Gene/Bank of the Y-chromosome (YHRD) in the University of Medicine, Berlin, Germany. Gene Accession Numbers of (YA003522) and (YA003523) for The Arabian Genetic Map, 2009. (www.yhrd.org/search). DNA GeneBanks (NCBI/EMBL/DDBJ) www.ncbi.nlm.nih.gov -Genbank accession number:AB588124 -Genes(s)16r RNA gene - Genetic platform :Streptomyces coelicolor 2011 -GeneBanks: YHRD www.yhrd.org/Search -Genbank accession number :YA003522 -Gene(s):17 genes cluster -Genetic platform: Arabian Genetic Map of Y-chromosome, 2009 -YHRD www.yhrd.org/Search -Genbank accession number: YA003523 -Gene(s): 17 genes cluster -Genetic platform:Arabian Genetic Map of Y-chromosome, 2009
Awards and Recognitions: 1. Award of American Gold Medal of Honor for Distinguished Leadership, American Biographical Institute, USA, 2002. 2. Award Certificate for Distinguished Leadership, American Biographical Institute, USA, 2002. 3. Award Certificate of New York Academy of Sciences, USA for Outstanding Contribution in Research and Community Services, 1997. 4. Colleague affiliation of Nobel-Prize Holders, New York Academy of Sciences, USA, 1997. 5. Award Certificate of Research Board of Advisors , American Biographical Institute, USA, 2002. 6. Honorary Appointment to the Research Board of Advisors, American Biographical Institute, USA, 2002. 7. ORS Award (Overseas Research Award of British Universities), England, 1985. 8. ORS Award (Overseas Research Award of British Universities), England, 1986. 9. Award of Scientific Distinction, Yarmouk University), Jordan, 1984. 10. Award of Scientific Distinction of His Majesty King Hussein), Jordan, 1984. 11. Certificate of Recognition and Outstanding services in Mu'tah, Jordan. 1988-2000. 12. Certificate of Recognition and Outstanding services in Al-al-Bayt University, Jordan, 1994-2005. 13. Certificate of Distinction and Outstanding , University of Qatar, 2001-2005. 14. Certificate of Recognition and Outstanding services in Sharjah University 15. International Consultations in Biotechnology & Genetic Engineering: (UNESCO, UNDP, ALESCO, ESESCO, European Commission), 1990-present.
• Community Services organization & supervision: More than 500 events during the period of (2011-2016) in the (5) branches of the Community Colleges (Sharjah, Maleha, Khorfakan, Kalba, Dibba), University of Sharjah. • Public lecturing & international speaker: more than (100). • International & regional consultations: more than (50).
• To promote Self-learning approach based on practical, observations, analysis and discussion • To educate student how acquire skills of knowledge production rather than to intake information. Teaching: During the last 28 years, I have taught both Undergraduates (a total of (33courses) & (7 courses) for the Postgraduates: (Gene testing, Gene Therapy, Advanced Biotechnology , Advanced Genetic Engineering, Advanced Experiments in Biotechnology, Advanced Cell and Tissue Culture, Advanced Marine Biotechnology.
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