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Dr.Hassen Hadj Kacem Academic RankAssociate Professor


  • Health Biotechnology, Molecular Biology, Human Genetics, High Throughput Analysis, Bioinformatics

Research Interests:

  • 1. Molecular genetics of endocrine diseases 2. Identification of Thyroid diseases Biomarkers 3. DNA technologies and Food authentication


Habilitation accreditation to supervise scientific research. National school of Engineers, Sfax University, Tunisia, 2011 Ph.D. Human Molecular Genetics/ BioEngineering, National School of Engineers of Sfax, TUNISIA, 2004. M.Sc. BioEngineering, National School of Engineers of Sfax, TUNISIA, 1999. Engr. BioEngineering, National School of Engineers of Sfax, TUNISIA, 1997.
2000- Faculty of Sciences, University of Sfax (Tunisia), Department of life sciences, Graduate teaching assistants. 2004- Medicine School, University of Sfax (Tunisia), Laboratory of Human Molecular Genetics, Young Researcher. 2005- Cochin Institute, University René Descart, Paris V (France), Department of genetics and development of molecular pathology (GDPM), Young Researcher (PostDoc ). 2006- Centre of Biotechnology of Sfax (Tunisia), Targets for diagnosis and therapy unit, Assistant Professor. 2012-2015 Centre of Biotechnology of Sfax (Tunisia), Microorganisms and Biomolecule Laboratory, and Molecular and Cellular Screening Process Laboratory, Associate Professor 2015- Associate Professor at Applied Biology, College of Sciences, University of Sharjah.
1. Molecular genetics of monogenic endocrine diseases caused by pituitary gland dysfunction 2. Genomic and Transcriptomic profiling of Human Thyroid cells 3. Transcriptomic profiling of Human lung cells 4. Development of DNA based protocols for food control and diagnosis
Héla Gargouri, · Nizar Moalla, · Hassen Hadj Kacem. PCR–RFLP and species-specific PCR efficiency for the identification of adulteries in meat and meat products. European Food Research and Technology (2021), Khan AA, Huat TJ, Al Mutery A, El-Serafi AT, Kacem HH, Abdallah SH, Reza MF, Abdullah JM, Jaafar H. Significant transcriptomic changes are associated with differentiation of bone marrow-derived mesenchymal stem cells into neural progenitor-like cells in the presence of bFGF and EGF. Cell Biosci. 2020 Oct 28;10:126. doi: 10.1186/s13578-020-00487-z. PMID: 33133516; PMCID: PMC7594431. Moalla M, Hadj Kacem F, Al-Mutery AF, Mahfood M, Mejdoub-Rekik N, Abid M, Mnif-Feki M, Hadj Kacem H. Nonstop mutation in the Kisspeptin 1 receptor (KISS1R) gene causes normosmic congenital hypogonadotropic hypogonadism. J Assist Reprod Genet. 2019 May 9. doi: 10.1007/s10815-019-01468-z. Hela Gargouri and Hassen Hadj Kacem. Evaluation of alternative DNA extraction protocols for the species determination in turkey salami authentication tests. International Journal of Food Properties. 2018, VOL. 21, NO. 1, 733–745 Tlili A, Al Mutery A, Kamal Eddine Ahmad Mohamed W, Mahfood M, Hadj Kacem H. Prevalence of GJB2 Mutations in Affected Individuals from United Arab Emirates with Autosomal Recessive Nonsyndromic Hearing Loss. Genet Test Mol Biomarkers. 2017 Nov;21(11):686-691. Rihab Kallel-Bouattour, Salima Belguith-Maalej, Emna Zouari-Bradai, Mouna Mnif, Mohamed Abid, Hassen Hadj Kacem. Intronic variants of SLC26A4 gene enhance splicing efficiency in hybrid minigene assay. Gene, Volume 620, 15 July 2017, Pages 10–14 Chakchouk I, Ben Said M, Jbeli F, Benmarzoug R, Loukil S, Smeti I, Chakroun A, Gibriel AA, Ghorbel A, Hadjkacem H, Masmoudi S. NADf Chip, a Two-Color Microarray for Simultaneous Screening of Multigene Mutations Associated with Hearing Impairment in North African Mediterranean Countries. J Mol Diagn. 2015 Mar;17(2):155-61. doi: 10.1016/j.jmoldx.2014.11.003. Epub 2015 Jan 2. PubMed PMID: 25560255.
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