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Dr.Hassen Hadj Kacem Academic RankAssociate Professor


  • Health Biotechnology, Molecular Biology, Human Genetics, High Throughput Analysis, Bioinformatics

Research Interests:

  • Genetic Biomarkers of Human Diseases, Endocrine Pathologies, Genomic Authenticity Testing


Habilitation accreditation to supervise scientific research. National school of Engineers, Sfax University, Tunisia, 2011 Ph.D. Human Molecular Genetics/ BioEngineering, National School of Engineers of Sfax, TUNISIA, 2004. M.Sc. BioEngineering, National School of Engineers of Sfax, TUNISIA, 1999. Engr. BioEngineering, National School of Engineers of Sfax, TUNISIA, 1997.
2000- Faculty of Sciences, University of Sfax (Tunisia), Department of life sciences, Graduate teaching assistants. 2004- Medicine School, University of Sfax (Tunisia), Laboratory of Human Molecular Genetics, Young Researcher. 2005- Cochin Institute, University René Descart, Paris V (France), Department of genetics and development of molecular pathology (GDPM), Young Researcher (PostDoc ). 2006- Centre of Biotechnology of Sfax (Tunisia), Targets for diagnosis and therapy unit, Assistant Professor. 2012-2015 Centre of Biotechnology of Sfax (Tunisia), Microorganisms and Biomolecule Laboratory, and Molecular and Cellular Screening Process Laboratory, Associate Professor 2015- Associate Professor at Applied Biology, College of Sciences, University of Sharjah.
2000-2002 PhD student: Collaborative Research Programme (CRP) of the International Centre for Genetic Engineering and Biotechnology: contract N : 99/015, Ref N°: CRP/TUN 99-02. Title: Susceptibility gene localisation in Thyroid autoimmune diseases. 2005-2007 Co-Investigator: Collaborative Research Programme (CRP) of the International Centre for Genetic Engineering and Biotechnology: Ref N°: CRP/TUN 04-02. Titlle: Molecular study of susceptibility genes to autoimmune diseases. 2007-2008 Member of CBS (TUNISIA) / 'University of Tsukuba (JAPAN) collaborative project "Analysis of the intracellular trafficking of three Tunisian natural pendrin mutants". 2008-2009 Principal Investigator: Spanish international Cooperation Agency (AECI). Ref N°: A/8301/07. Title: Analysis of the genetic factors associated to Thyroid pathologies. 2012-2014 Co-investigator: ICGEB (International Centre for Genetic Engineering and Biotechnology) "Microarray-based system for the detection of North African mutations".
Chakchouk I, Ben Said M, Jbeli F, Benmarzoug R, Loukil S, Smeti I, Chakroun A, Gibriel AA, Ghorbel A, Hadjkacem H, Masmoudi S. NADf Chip, a Two-Color Microarray for Simultaneous Screening of Multigene Mutations Associated with Hearing Impairment in North African Mediterranean Countries. J Mol Diagn. 2015 Mar;17(2):155-61. doi: 10.1016/j.jmoldx.2014.11.003. Epub 2015 Jan 2. PubMed PMID: 25560255. Belguith-Maalej S, Kallel R, Mnif M, Abid M, Ayadi H, Kacem HH. Association of intronic repetition of SLC26A4 gene with Hashimoto thyroiditis disease. Genet Res (Camb). 2013 Feb;95(1):38-44. doi: 10.1017/S0016672313000037. Epub 2013 Mar 4. PubMed PMID: 23452581. Kallel R, Niasme-Grare M, Belguith-Maalej S, Mnif M, Abid M, Ayadi H, Masmoudi S, Jonard L, Hadj Kacem H. Screening of SLC26A4 gene in autoimmune thyroid diseases. Int J Immunogenet. 2013 Aug;40(4):284-91. doi: 10.1111/iji.12035. Epub 2012 Dec 22. PubMed PMID: 23280318. Rihab Kallel, Salima Belguith-Maalej, Abdelmounaim Akdi, Mouna Mnif, Ilhem Charfeddine, Pere Galofré, Abdelmonaim Ghorbel, Mohamed ABID, Ricard Marcos, Hammadi Ayadi, Antonia Velazquez and Hassen Hadj Kacem. Genetic investigation of FOXE1 polyalanine tract in thyroid diseases: New insight on the role of FOXE1 in thyroid carcinoma. Cancer Biomark. 2010-2011;8(1):43-51. doi: 10.3233/DMA- 2011-0824. BELGUITH-MAALEJ Salima, REBUFFAT Sandra A, CHARFEDDINE Ilhem, MNIF Mouna, NADIR R Farid, ABID Mohamed, GHORBEL Abdelmoneem, PERALDI-ROUX Sylvie , AYADI Hammadi and HADJ-KACEM Hassen. SLC26A4 expression among autoimmune thyroid tissues. Immunobiology. 2011 May;216(5):571-8. Epub 2010 Oct 28. PMID:21035230
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