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Dr.Khalid Bajou Academic RankAssociate Professor

Specialization:

  • Biochemistry and Cell biology

Research Interests:

  • 1. Cancer biology: angiogenesis, tumor microenvironment, metastasis and tumor animal models. 2. Cardiovascular diseases: Thrombosis and thrombolysis.

Contact

Ph.D. in Science, October 25, 2001, University of Liège, Liege, Belgium. Dissertation title: Role of Plasminogen Activator Inhibitor-1 in tumor invasion and angiogenesis. (Supervisor, Professor J.M. Foidart). Master in Molecular and Cellular Biology, June 1992, University of Liège, Liege, Belgium
Assistant Professor, the Interdisciplinary Cluster for applied Genoproteomics (GIGA) Research Center, Cancer Department, College of Biomedical Science, University of Liege, Liege, Belgium, since July 2007. Postdoctoral fellow with Prof. Yves A. DeClerck, Division of Hematology-Oncology, Department of Pediatrics, Children’s Hospital Los Angeles, University of Southern California, Los Angeles. November 2002 – Jun 2007. Postdoctoral fellow with Prof. Agnes Noel, Department of Tumor and Developmental Biology, University of Liège, Liege, Belgium. October 2001 – October 2002. Ph. D student with Prof. Jean Michel Foidart, Department of Tumor and Developmental Biology, University of Liège, Liege, Belgium. September 1995 – September 2001. Research Position with Prof. Jose Remacle, Department of Biochemistry and Cellular Biology, University of Namur, (Belgium). October 1992 – August 1995.
- American Association for Cancer Research (active member). - The International Society on Thrombosis and Haemostasis (regular member) - International Proteolysis Society (regular member) - Belgian Association for Cancer Research (regular member) - Belgian Society for Cell and Developmental Biology (regular member)
1-Targeting PAI-1 in tumor angiogenesis and metastasis using 14K fragments of growth hormone, 16K fragments of prolactin and their derived peptides. 2-PAI-1 in tumor angiogenesis and metastasis
Alomran, S.S., Khan,M., Khan,A., Abdallah,S., Fayyad,A. Bajou K. miR-22-3p Suppresses Adipocyte Formation of Telomerase Transformed Mesenchymal Stromal Cells (iMSC3) by Regulating Non-targeted MAPK Signaling Pathway. Pakistan J. Zool., pp 1-9, 2021. DOI: https://dx.doi.org/10.17582/journal.pjz/20191127131153 Elgamouz, A., Idriss, H., Nassab, C., Bihi, A., Bajou, K., Hasan, K., Abu Haija, M., Patole, S.P. Green Synthesis, Characterization, Antimicrobial, Anti-Cancer, and Optimization of Colorimetric Sensing of Hydrogen Peroxide of Algae Extract Capped Silver Nanoparticles. Nanomaterials. 2020 Sep 17;10(9):E1861. doi: 10.3390/nano10091861. Elgamouz, A., Alsaidi, R., Alsaidi, A., Zahri, M., Almehdi, A., Bajou, K. Dataset in the characterization of black spot Ehrenberg snapper and its proteins' denaturation inhibition by natural antioxidants. Data Brief. 2019 Dec 5;28:104927. doi: 10.1016/j.dib.2019.104927. eCollection 2020 Feb Elgamouz, A., Alsaidi, R., Alsaidi, A., Zahri, M., Almehdi, A., Bajou, K. The Effects of Storage on Quality and Nutritional Values of Ehrenberg's Snapper Muscles (Lutjanus Ehrenbergi): Evaluation of Natural Antioxidants Effect on the Denaturation of Proteins. Biomolecules 2019, 9, 442; doi:10.3390/biom9090442 Fayyad,A., Khan,A., Abdallah,S., Alomran,S., Bajou,K. and Khan,M. Rosiglitazone enhances Browning Adipocytes by activating MAP kinase and PI-3 Kinase pathways during the in vitro differentiation of telomerase-transformed Mesenchymal stem cells into Adipocytes. Int. J. Mol. Sci. 2019, 20, 1618; doi:10.3390/ijms20071618 Tlili, A., Fahd Al Mutery, A., Mahfood, M., Kamal Eddine Ahmad Mohamed, W., Bajou, K. Identification of a novel frameshift mutation in the ILDR1 gene in a UAE family, mutations review and phenotype genotype correlation. PLoS One. 2017 Sep 25;12(9):e0185281. doi: 10.1371/journal.pone.0185281. eCollection 2017. Herkenne,S., Paques,P., Nivelles,N., Lion,M., Bajou,K., Pollenus,T., Fontaine,M., Carmeliet,P., Martial,J., Nguyen,N.Q.N., Struman,S. The interaction of uPAR with VEGFR2 promotes VEGF-induced angiogenesis. Sci. Signal. 2015 Nov 17;8 (403):ra117 Bajou,K., Herkenne,S., Thijssen,V.L., D'Amico,S., N.guyen,N.Q.N., Bouché,A., Tabruyn,S., Srahna,M., Carabin,J.V., Nivelles,O., Paques,C., Cornelissen,I., Lion,M., Noel,A., Gils,A., Vinckier,S., Declerck,P.J., Griffioen,A.W., Dewerchin,M., Martial,J.A., Carmeliet,P. and Struman,I. PAI-1 mediates the anti-angiogenic and pro- fibrinolytic effects of 16K prolactin. Nat.Med., 2014 jul, 20, 741-747. Amand,M., Erpicum,C., Bajou,K., Cerignoli,F., Blacher,S., Martin,M., Dequiedt,F., Drion,P., Singh,P., Tinatin,Z., Vandereyken,M., Musumeci,L., Mustelin,T., Moutschen,M., Gilles,C., Noel,A. and Rahmouni,S. DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase Molecular cancer, 2014, 13, 1-08
A pharmaceutical composition for treatment of thrombosis-related diseases comprising a fragment of prolactin (PRL)-growth hormone(GH) - placental lactogen (PL)-family protein., EP 2356998 A1, US20130035289, 2010, Europe. Struman,I., Bajou,K., D’Amico,S., Martial,J. University of Liege.
Van Beirs Prize, Fonds Léon Fredericq, Liege, Belgium, 2002. Lions Club Prize, University of Liege, Liege, Belgium, 2002 Adolphe Wetrems Prize, by the Royal Academy of Science, Literature and Art of Belgium, Brussels, Belgium, 2001. Alvarenga de Piauhy Prize by the Royal Academy of Medicine of Belgium, Brussels, Belgium. 2001. Best Poster Prize by the American Association for Cancer Research (Travel Grant Award), Nyborg, Denmark, June 14-18, 1998. Travel Award by AACR-AstraZeneca, American Association for Cancer Research, 97th Annual Meeting, Washington DC: April 1-5, 2006. Travel Award by The Gorgon Research Conferences, Plasminogen Activation and Extracellular Proteolysis, Ventura, CA: February 8-13, 2004. Post-Doc Fellowship Award by Rose and Jean Hoguet Foundation, Brussels, Belgium, 2002-2003, 2003-2004. Post-Doc Fellowship Award by the “CENTRE ANTICANCEREUX” Liège, Belgium, 2002 Post-Doc Fellowship Award by the “KANKEROLOGISCHE STICHTING ST-MICHIEL V.Z.W.” Foundation, Brussels, Belgium, 2002. Post-Doc Fellowship Award by the Rotary International District 1630, Belgium, 2002. Post-Doc Fellowship Award by the “Mr et Mm F. Braconnier-Lamarche”, Liege, Belgium, 2002. Travel Fellowship Award by “Agathon De Potter Foundation”, the Royal Academy of Science, Literature and Art of Belgium, Brussels, Belgium, 2002. Ph.D Fellowship Award by the “Fonds National de la Recherche Scientifique” (FNRS), Belgium. October 1997 – September 2001: Ph.D Fellowship Award by the “Centre Anticancereux” Liège, Belgium. October 1996 – September 1997:
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