Bachelor of Science in Biotechnology

1450101

General Biology (1)

Prerequisite:

-

This course includes topics concerned with the cell biochemistry, structure, function, respiration and photosynthesis. The cell cycle and its control in addition to the division of animal and plant cells will be discussed. Classical and molecular genetics will be emphasized. Also, animal and plant tissues will be introduced.

1450107

General Biology Lab

Prerequisite:

Pre/Co 1450101

The course is designed to introduce students to many of the fundamental concepts in biology. Experiments are presented in a “hands-on” environment illustrated by the use of the microscope and observable physical and chemical reactions to study the principals of cell structure and functions of plant and animal cells. This lab course will, also, be devoted to cellular respiration, division and genetics. The last section will focus on the study of animal tissues in addition to the human anatomy.

1450102

General Biology (2)

Prerequisite:

1450101

This course will cover wide range of conceptual knowledge of both molecular level from molecular basis of inheritance from gene to protein synthesis, gene replication, gene regulation, gene expression (transcription & translation) up to the selected body systems function & structure. The course also covers the viral genomics DNA vs. RNA types & variants, phylogenetic, life cycle, infectious spectrum & pandemics. Examples on the principles of viral applications in biotechnology will be given including gene transfer & vaccine production platforms. The course also introduces the basic principles of selected examples on various spectrum of biotechnology on microbial, plant, animal, environmental, gene editing gene therapy.

1450201

Basic Biotechnology

Prerequisite:

1450102

This course discusses the fundamental aspects of biotechnology and its importance to mankind in a concise and lucid explanation of this newly founded science. The course emphasizes how cell structure and function is a vital starting point for knowledge of genetic engineering and gene technology. Lectures will underlie the principles and application of Recombinant DNA technology in industrial, agricultural, pharmaceutical, and biomedical fields. Lecture will also include the fermentation systems for commercial production of useful products and their purification.

1450251

Cell Biology

Prerequisite:

1450102

In this course the following topics will be covered: Introduction to the world of cell; brief description of unity and diversity of cells; evolution of cell from simple molecules; the structure and function of cell membrane and the transport of small molecules across the membrane; structure and function of different organelles and protein targeting to these organelles; introduction to cytoskeletal proteins and

extra cellular matrix; eukaryotic cell cycle and cancer.

1450331

General Microbiology

Prerequisite:

1450251

General Microbiology is a 3-credit course that introduces the students to the microbial world, but will emphasize bacteria. The course will cover bacterial cell structure and function, microbial nutrition, growth, and methods of controlling of microbial growth. Classification of microorganisms, diversity of prokaryotes, principles of the interrelationships of microorganisms and man, and their role in the environment are other key topics of the course.

1450332

General Micro. Lab

Prerequisite:

Pre/Co 1450331

The laboratory is designed to provide practical and hands-on experience of a variety of microbiological techniques. Laboratory work includes microscopy, staining, aseptic and sterile transfer techniques, assessment of morphological and biochemical properties of microorganisms and microbial identification.

1450333

Immunology & Serology

Prerequisite:

1450251

The course describes the fundamental aspects of immunology. Antigen and antigenicity. Antibody structure, function, and diversity. Cell and organs of immune system. Humoral and cellular immune response. Complement and phagocytosis. Immunity against infectious pathogens and tumors. Immunodeficiency and AIDS, hypersensitivity, autoimmunity, and transplantation.

1450336

Immunology and Serology Lab

Prerequisite:

Pre/Co 1450333

The objective of this course is to introduce experimental design and basic and advanced techniques commonly used in immunology research laboratories. The course provides basis for popular immunological techniques like ELISA, immunofluorescence, flow cytometry and serum protein electrophoresis.

1450341

Molecular Genetics

Prerequisite:

1450251

This course aims to introduce students to the fundamental principles of genetics in eukaryotes and prokaryotes and to basic molecular genetics analysis used in biotechnology. Topics will include Mendelian and non-Mendelian inheritance, sex-linked traits, linkage, recombination, bacterial and viral genetic systems, control of gene expression in bacteria and molecular genetic analysis in biotechnology.

1450342

Molecular Genetics Lab

Prerequisite:

Pre/Co 1450341

This course is an introduction to many areas of modern genetics and emphasizes the principles of genetics in each of two main areas, transmission, and molecular genetics. Different model organisms will be studied and analyzed by students to understand the segregation of mendelian and non-mendelian genes, as well as sex-linked traits. Moreover, experiments of the three main modes of gene’s transfer in bacterial genetics (conjugation, transformation, and transduction) will be conducted. Furthermore, students will study and investigate the inducible expression of Lac operon genes in prokaryotes. Finally, they will perform different molecular genetics experiments used in the different fields of Biotechnology.

1450301

Bioinformatics

Prerequisite:

1411100+1411116

This course will introduce students to biological databases especially GenBank at the NCBI in addition to some of the most commonly used software and tools for genetic analysis of nucleic acid, protein sequences and designing primers and probes for conventional and quantitative PCR. In addition, the class explores and explains some of the computational biology tools found on the Internet and how they can be applied to problems in genomics and molecular biology.

1450351

General Biochemistry

Prerequisite:

1426217+1450251

The course is designed to provide an understanding of the structure of the chemical components of living matter. Topics covered include chemical principles of biologic systems; water, amino acids, proteins (protein structure and stability); introduction to steady-state kinetics; enzyme mechanism; controlling enzyme activity; metabolic circuitry; glucose transport and metabolism; pyruvate metabolism; citric acid cycle; electron flow and

oxidative phosphorylation; glycogen metabolism; gluconeogenesis and the pentose shunt; fatty acid catabolism and synthesis; disposal of nitrogen: the urea cycle; amino acid catabolism and synthesis.

1450352

General Biochemistry Lab

Prerequisite:

Pre/Co 1450351

The aim of this Laboratory course is to provide an introduction to general laboratory techniques routinely used in Biochemistry with emphasis on the qualitative as well as quantitative aspects of the biochemical experiments. The course deals with principles and practices of Biochemistry, chromatography for the investigation of metabolites, proteins, polysaccharides, application of enzymes for quantitative determinations by spectroscopic methods, and introductory experiments about kinetics of enzyme action.

1450361

Tissue Culture & Animal Biotech

Prerequisite:

1450332+1450333

This course provides insights into the application of animal tissue culture. It is designed to familiarize you with the basic principles and training in cell culture techniques that are widely used in modern research laboratories and bio-industries. The course involves correlation between the theory and practical to ensure full understanding of the techniques. The establishment and requirements of the basic concepts of totipotency, organized growth, growth regulator types and functions and the different factors that affect the success of the culture will be emphasized in the theoretical part. In the laboratory part the establishment, maintenance and subculture of animal cells will be a major task. The course will also introduce the student to basic hybridoma technology and isolation of monoclonal antibodies.

1450431

Microbial processing & Biotechnology

Prerequisite:

1450201+1450331

The course focuses on the wide scope of the biotechnological applications & processing of industrial microbiology. It is aimed to highlight the potential of wild-type or genetically modified microorganisms as cell factories for the production of products and services. It introduces the student to the modern microbial biotechnology with the several areas of industrial application of microorganisms as production of antibiotics & other medico-pharmaceuticals, protein production (hormones, enzymes, antibodies, vaccines, SCP), production of biochemical (primary/secondary metabolites, organic acids, amino acids), applications in food and beverage technology, agriculture and environmental biotechnologies and alternative energies (bioenergy), downstream processing technology.

1450436

Environmental Biotechnology

Prerequisite:

1450201+1450331

This course gives an overview of the fundamental components of the science needed to address environmental problems such as detection of pollutants, elimination and treatment of toxic wastes, development of environment friendly products and improved energy sources. Students will learn specific applications of metabolic capability and molecular biology of microorganisms to degrade environmental contaminants and remediate environmental media will be discussed. Biofuel production will be discussed with an emphasis on cleaner and sustainable environment.

1450451

Molecular Biology

Prerequisite:

1450341

A lecture course dealing with the molecular nature of genes and genomes and analysis of the biochemical processes (homologous recombination, transcription, RNA splicing, and translation) involved in expression and regulation of prokaryotic and eukaryotic genes.

1450452

Molecular Biology Lab

Prerequisite:

Pre/Co 1450451

This course is designed to enhance the preparation of students for careers in research, biotechnology and science education. The laboratory experience will introduce students to the field of molecular biology where they will learn all the basic methodologies and instrumentation commonly used in biotechnology and molecular biology laboratories. Students will learn bacterial transformation, plasmid DNA purification, restriction digestion and ligation along with gel electrophoresis, polymerase chain reaction (PCR), cloning DNA fragments, and selection of recombinants. This course will give students who plan career in research or biotechnology practical experience that mimics the realities of the laboratory setting.

1450421

Plant Biotechnology

Prerequisite:

1450201

This course presents an overview of the genetic principles and techniques used in plant modification. Starting with a general background about the mendelian genetics and plant sexual reproduction, then explaining the conventional methods of plant breeding. Moving to the modern techniques used in plant molecular breeding. Plant tissue culture and genetic engineering methods used to develop transgenic plants will be emphasized. The course is also discussing the controversy over transgenic plants and their risk assessment. Patents and intellectual property issues will be also highlighted in the course. The course format is a combination of lectures, laboratory, visits, and projects. Two field trips that will emphasize different application of plant biotechnology will also be included.

1450441

Molecular Human Genetics

Prerequisite:

1450341

In this course you will learn about a dynamic field that is expanding very rapidly and is directly concerning human biology and general health. The course deals with the mode of inheritance of human genes, structure and organization of the human genome, mapping of the human genome, the technology behind sequencing the human genome, instability of the human genome, identifying human disease genes, genetic testing in individuals, genetic manipulation of animals for modeling disease and investigating gene function.

1450491

Seminar

Prerequisite:

Pre/Co 1450451

This one credit course is meant to give students practice speaking in front of a scientific audience and to explore topics in detail.Students will search topics and organize presentations for faculty and other students. The topics may be a recently published scientific paper or breaking news in the field of biotechnology. The topic must be approved by the instructor in advance. The student should prepare the slides and presented the topic in the following order: abstract, introduction objectives, materials and methods, results, discussion, conclusions and references.

1450493

Research Project

Prerequisite:

99 C.H

A well-defined problem is assigned to the student in order to carry out experimental work to be presented in an acceptable form of a scientific report. Generally, the supervisors have set of problems/themes for the students to choose. Students in the form of group of three or more will discuss and agree for the project with respective supervisors.

1450496

Ethical Aspects of Biotechnology

Prerequisite:

1450201

This course will focus on discussing what is morally right or wrong in the practice of biotechnology. The applications of modern biotechnology impinge upon some of the most fundamental of human situations – our health, our food, our environment – they raise serious questions in our minds. The ethics of the following issues will be discussed: Fertility and morality; research on human embryo and embryonic stem cells; genomic, eugenics and integrity; experiments on animal and bioethics and environment.

1450334

Microbial Genetics

Prerequisite:

1450332+1450341

Theory part: The course covers a wide scope of both prokaryotic and eukaryotic microbial genetic systems including microbial modules, genetic complexity, gene-interplay regulation, Quorum & sigma regulation systems. The course covers the Lateral/Horizontal genetic transfer (LGT/HGT) processes in bacteria such as conjugation, transformation and transduction, gene manipulation, recombination, cloning, expression, phylogenetic analysis of microbial genetics, mutations & mutagenesis, and the latest discovery of CRISPR-Cas9-gene-editing in the streptococcus pyogens. The viral DNA/RNA complexity with relations to the epidemics will be covered also.

Practical platform, in the laboratory, student will develop their practical skills on genetic complexity & the Lateral/Horizontal genetic transfer (LGT/HGT) processes in bacteria such as conjugation, transformation and transduction, CRISPR-Editing, & visit to the human insulin production unit in Julphar, industry. The practical includes training microbial DNA isolation, purification, quantitation, standardization, optimization, restriction mapping, cloning & expression using Lux-gene cluster (vibrio fischeri) & GRP-gene cluster (Aquaria victoria) with different plasmids such as pVIP, pGLO, pBR322.

450455

Biotechnology in Medicine

Prerequisite:

1450341

This course will focus on the uses of modern biotechnology in the areas of medicine, from making vaccines and drugs to determining genetic origins of diseases, producing organs for xeno-transplant and developing nano-medical diagnostic methods. The student will be exposed to genetic counseling training, based on studying and writing a report on selected cases that address specific genetic diseases and their outcomes.

1450437

Pharmaceutical Biotechnology

Prerequisite:

1450201

This course presents an overview of the concepts and applications of the pharmaceutical biotechnology. The course is highlighting the basic principles of protein structure, and describing in details the concepts and methods for recombinant drug production with special focus on downstream and upstream processing and product analysis. It also increases/extends the focus upon topics such as formulation and delivery of biopharmaceuticals, and it contains case studies in which both biotech and clinical aspects of a particular approved product of pharmaceutical biotechnology are overviewed. Recent applications of pharmaceutical biotechnology are also discussed. The course format is a combination of lectures, visits, and projects.

1450311

Intro. to Forensic Sciences

Prerequisite:

1450102+1426155

This course introduces the basic principles and relationships between the applications of chemistry, biology, and physics to forensic science as they relate to the criminal investigative process. The course is designed to give students insight into the many areas of forensic science and to study the newest techniques used by forensic laboratories. Topics discussed include organic and inorganic chemical analyses of physical evidence, principles of serology and DNA analysis, identification of fresh and decomposed human remains, fingerprint analysis, drug analysis, and forensic entomology.

1450391

Scientific Writing and Presentation

Prerequisite:

0202103+1450201

This class outlines the basic requirements for science essaysandoral presentations. Itcovers thebasictools of writingsuch as illustrations and references. Students learn how to writeascientific paper,agrantproposal,andhow to prepare ascientificposter.Curriculum vitaeandcover letterswill alsobe addressed.