Sign In
Skip Navigation Links.
Expand AboutAbout
Our People
Expand Quick LinksQuick Links
Expand MediaMedia
Prof.Iman Saad Ahmed Academic RankProfessor

Specialization:

  • Pharmaceutics, Biopharmaceutics & Pharmacokinetics

Research Interests:

  • My research interest takes three basic thrusts within the areas of biopharmaceutics, pharmacokinetics, and drug targeting. Motivated by real applications, my research evolved since then to include the use of nanotechnology in the development of innovative drug delivery systems that alter the PK/PD response of different classes of drugs and reduce their systemic side effects. More recently my research evolved to include modeling-based drug development using PK/PD models to improve drug efficacy, patient’s compliance and reduce drug toxicity.

Contact

•Ph.D., College of Pharmacy, Oregon State University, USA, 2002 •Minor in statistics •M.Sc., Faculty of Pharmacy, Cairo University, 1991 •B.Sc., Faculty of Pharmacy, Cairo University, 1985
2020-To Date Vice Dean, College of Pharmacy, University of Sharjah, Sharjah, UAE 2020-To Date Professor of Pharmaceutics, College of Pharmacy, University of Sharjah, Sharjah, UAE 2014- 2019 Professor of Pharmaceutics, Faculty of Pharmacy, Cairo University, Egypt 2008-2019 Associate Professor of Pharmaceutics, College of Pharmacy, University of Sharjah, Sharjah, UAE 2012-2017 Head of Department of Pharmaceutics & Pharmaceutical Technology, College of Pharmacy, University of Sharjah, Sharjah, UAE 2007-2013 Associate Professor of Pharmaceutics, Faculty of Pharmacy, Cairo University, Egypt 2009-2011 Head of Department of Pharmacology & Pharmaceutics, College of Pharmacy, University of Sharjah, Sharjah, UAE 2002-2007 Assistant Professor of Biopharmaceutics & Pharmacokinetics, Cairo University, Egypt
•Teaching, scientific research, and academic collaboration with world universities. •Project design, formulation development of an oral protein delivery system and management of clinical trials, Allergenics, Inc., South San Francisco. •Joint-scientific and research collaboration on the development of innovative drug delivery systems, Oregon State University-GlaxoSmithKline, RTP, North Carolina. •Consultancy at CBiC Co., Egypt, in the training and development section. Preparing and teaching courses that cover various technical issues in the drug industry. •Organizing and teaching workshops in drug stability and bioequivalence. •Presentation of scientific papers in many national and international conferences. •International scientific collaboration with Toyama University, Japan. •International scientific collaboration with University of Montreal, Canada.
· The Egyptian Pharmaceutical Society · Egyptian Syndicate of Pharmacists · American Association of Pharmaceutical Scientists (AAPS)
•Construction of Pop-PK models for methylphenidate to describe its pharmacokinetic profile when given in combined immediate release and controlled release doses. •Development of buccoadhesive controlled-release dosage forms and orally-disintegrating lyophilized tablets to improve the bioavailability of drugs via the buccal route. •Development of colonic delivery systems for site-specific drug delivery to the colon. •Development of gastric retention formulation to enhance the oral bioavailability of drugs with limited absorption or drugs used for local action in the stomach. •Enhancing drug delivery to the liver through nanoparticles mediated dual targeting. •Development and optimization of oral atorvastatin-loaded nanoparticles to increase the efficacy and improve the safety profile of statins. •Prediction of the area under the curve of cyclosporine using regression limited sampling strategies. •Development and optimization of nanocrystals of certain antibiotics as a novel approach to treat skin infections. • Foreigner visiting researcher in the Department of Pharmacometrics, Faculty of Pharmacy, University of Montreal, Montreal, Canada. (Chairman: Professor/Fahima Nekka). Research project title: “Construction of Pop-PK models for methylphenidate to describe its pharmacokinetic profile when given in combined immediate release and controlled release doses. • Foreigner visiting researcher in the Department of Radiological Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan. (Chairman: Professor/Takashi Kondo). Research project title: “Sonotransfection as a tool in cancer therapy; Optimization and possible application in multidrug resistance”.
1. Mutasem Rawas-Qalaji, Rawan Bafail, Iman Saad Ahmed, Mohammad Nasir Uddin, Sami Nazzal. Modulation of the sublingual microenvironment and pH-dependent transport pathways to enhance atropine sulfate permeability for the treatment of organophosphates poisoning (2021). Int. J. Pharm. 606, 120898. 2. M. Haider, A. Elsherbeny, J. Jagal, A. Hubatova-Vackova and I.S. Ahmed. Optimization and Evaluation of Poly(lactide-co-glycolide) Nanoparticles for Enhanced Cellular Uptake and Efficacy of Paclitaxel in the Treatment of Head and Neck Cancer (2020). Pharmaceutics, 12 (9), 828, pp. 1-22. 3. Iman S. Ahmed, Osama S. Elnahas, Nouran H. Assar, Amani M. Gad and Rania El Hosary. Nanocrystals of fusidic acid for dual enhancement of dermal delivery and anti-bacterial activity: In vitro, ex vivo and in vivo evaluation (2020). Pharmaceutics, 12(3), 199. 4. Iman S. Ahmed, Hassan M. Rashed, Hend Fayez, Faten Farouk, Rehab N. Shamma. Nanoparticle-mediated dual targeting: An approach for enhanced baicalin delivery to the liver (2020). Pharmaceutics, 12 (2), 107. 5. Carol Yousry, Iman S. Ahmed, Maha M. Amin and Omaima N. El Gazayerly. Superhydrophobic Substrates for Ultrahigh Encapsulation of Hydrophilic Drug into Controlled Release Polyelectrolyte Complex Beads: Statistical Optimization and In Vivo Evaluation (2019). Pharmaceutics, 11 (6), 257. 6. Mohamed Haider, Mariame A. Hassan, Iman S. Ahmed, Rehab Shamma. Thermogelling platform for baicalin delivery for versatile biomedical applications (2018). Mol. Pharm. 15 (18), 3478-3488. 7. Iman S. Ahmed, Rania EL-Hosary, Mariame Hassan, Mohamed Haider, Marwa M. Abd-Rabo. Efficacy and Safety Profiles of Oral Atorvastatin-Loaded Nanoparticles: Effect of Size Modulation on Biodistribution (2018). Mol. Pharm. 15 (11), 247-255. 8. Iman S. Ahmed, Rania EL-Hosary, Samia Shalaby, Marwa M. Abd-Rabo, Dalia G. ElKhateeb, Samia Nour. PD-PK Evaluation of Freeze-dried Atorvastatin Calcium-Loaded Poly--Caprolactone Nanoparticles (2016). Int. J. Pharm. 504, 70-79. 9. Sarem S, Nekka F, Ahmed IS, Litalien C, Li J. Impact of sampling time deviations on the prediction of the area under the curve using regression limited sampling strategies (2015). Biopharm. Drug Dispos. 36 (7), 417-428. 10. Iman S. Ahmed, Mariame A. Hassan, Takashi Kondo. Effect of lyophilized grapefruit juice on P-glycoprotein-mediated drug transport in-vitro and in-vivo (2015). Drug Dev. Ind. Pharm. 41 (3), 375-381. 11. Iman S. Ahmed, Mariame A. Hassan, Takashi Kondo. Effect of lyophilized grapefruit juice on P-glycoprotein-mediated drug transport in-vitro and in-vivo (2013). Drug Dev. Ind. Pharm. 12. Mariame A. Hassan, Iman S. Ahmed, Paul Campbell, Takashi Kondo. Enhanced gene transfection using Calcium Phosphate Co-precipitates and low-intensity pulsed ultrasound (2012). Eur. J. Pharm. Sci. 47, 768 773. 13. I.S. Ahmed and J.W. Ayres. Comparison of in vitro and in vivo performance of a colonic delivery system (2011). Int. J. Pharm. 409, 169 177. 14. R.A. Shoukri, I.S. Ahmed, R.N. Shamma. In vitro and in vivo evaluation of nimesulide lyophilized orally disintegrating tablets (2009). Eur. J. Pharm. Biopharm. 73, 162 171. 15. I.S. Ahmed, M. H. Abouel-Einien, O. H. Mohamed, S. F. Farid. Relative bioavailability of griseofulvin lyophilized dry emulsion tablet vs. immediate release tablet: A single-dose, randomized, open-label, six-period, crossover study in healthy adult volunteers in the fasted and fed states (2008). Eur. J. Pharm. Sci. 35, 219 225. 16. I.S. Ahmed and J.W. Ayres. Bioavailability of riboflavin from a gastric retention formulation (2007). Int. J. Pharm. 330, 146 154. 17. I.S. Ahmed and F.A. Fatahalla. Pilot study of relative bioavailability of two oral formulations of ketoprofen 25 mg in healthy subjects. A fast-dissolving lyophilized tablet as compared to immediate release tablet (2007). Drug Dev. Ind. Pharm. 33, 505 511. 18. I.S. Ahmed and M. H. Abouel-Einien. In vitro and in vivo evaluation of a fast-disintegrating lyophilized dry emulsion tablet containing griseofulvin (2007). Eur. J. Pharm. Sci. 32, 58 68.
•Supervising and completion of several Ph.D. thesis and Master thesis in the bith the Faculty of Pharmacy at Cairo University and the College of Pharmacy at the University of Sharjah.
• The Sharjah Islamic Bank Award 2017/2018 for Distinguished Research (AED 6000). • Annual Incentive Award for distinguished faculty members in the category of “Teaching” for the academic year of 2016/2017, University of Sharjah (AED15,000). • Annual Incentive Award for distinguished faculty members in the category of “Teaching” for the academic year of 2012/2013, University of Sharjah (AED15,000). • Best published paper award by the faculty of pharmacy 2010 for the paper “I.S. Ahmed, M. H. Abouel-Einien, O. H. Mohamed, S. F. Farid. Relative bioavailability of griseofulvin lyophilized dry emulsion tablet vs. immediate release tablet: A single-dose, randomized, open-label, six-period, crossover study in healthy adult volunteers in the fasted and fed states (2008). Eur. J. Pharm. Sci. 35, 219-225”.
• Vice-Dean of the College of Pharmacy • Chairperson of the Department of Pharmaceutics & Pharmaceutical Technology, University of Sharjah. • Chairperson of the Department of Pharmacology & Pharmaceutics. • Member of the college of pharmacy council, UoS. • Chair of the Program Evaluation and Quality Assurance Committee, College of Pharmacy, UoS. • Member of Institutional Effectiveness and Accreditation Committee, UoS • Chair of Professional Conduct Committee. • Member of the Taskstream implementation committee, UoS.
One of my main objectives of being a teacher is to foster and create an environment that allows my students to show their potential and interest in what they learn. Since learning is many times defined as a change of attitude, I make sure to have credibility to act as role model. Respecting different cultures while seeking to instill values reflecting the vision of the university is also one of my main objectives as a teacher. I am an advocate of active learning by using a variety of methods that contributes to creating a culture of inquiry and empower the students to take responsibility for their own learning such as TBL, group discussions, field visits, articles reading and group assignments or projects in which the students can engage in self-reflection on critical issues. Integrating research into teaching and learning is on top of my priorities to promote inter-disciplinarily, creativity and innovation among students. This will allow motivated students to experience the work of scientists through participating in analyzing, applying, discovering and validating knowledge. It also prepares students to be life-long learners and keeps them abreast of advances in science and technology. By adopting these learning/teaching techniques I hope to foster critical thinking, facilitate the acquisition of life-long learning skills, develop problem-solving strategies and prepare my students to function as highly skilled and competent pharmacist across the scope of practice and in my primary teaching area of pharmaceutics and pharmaceutical technology.
Back to list