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Dr.Zahid Hussain Academic RankAssociate Professor
Zahid Hussain

Specialization:

  • Pharmaceutics and Pharmaceutical Nanotechnology.

Research Interests:

  • • Polymeric Nanoparticles based drug delivery systems • Targeted Delivery of drugs using passive and active strategies • Cell culture (toxicity and specific uptake studies) • Ex vivo and in vivo animal models • Pharmacological, immunological and histological examinations

Contact

•Ph.D. Pharmaceutics, Universiti Kebangsaan Malaysia, Malaysia, 2014 •Pharm-D (Doctor of Pharmacy), University of Sargodha, Pakistan, 2008 •F.Sc. (Pre-medical), B.I.S.E, Gujranwala, Pakistan, 2003 •Matriculation (SSC), B.I.S.E, Gujranwala, Pakistan, 2000
Sep 2019 – to date: Assistant Professor, Department of Pharmaceutics and Pharmaceutical Technology, University of Sharjah, Sharjah, United Arab Emirates. May 2015 – Aug 2019: Senior Lecturer, Department of Pharmaceutics, Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, Malaysia. May 2015 – Aug 2019: Course coordinator for “Physicochemical Basis for Pharmacy” (PHC400), Department of Pharmaceutics, Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, Malaysia. Aug 2014 – April 2015: Lecturer, Faculty of Pharmacy, SEGi University, Kota Damansara Main Campus, Kuala Lumpur, Malaysia. Aug 2014 – April 2015: Module coordinator, (B-Pharm Program), Faculty of Pharmacy, SEGi University, Kota Damansara Main Campus, Malaysia. June 2013 – June 2014: Lecturer (Part-time), Department of Pharmacology, Faculty of Medicine, Lincoln University College, Petailing Jaya, Selangor Malaysia. Jan 2011 – Aug 2014: Research Assistant, Department of Pharmaceutics, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia. June 2008 – Dec 2010: Executive Regional Sales officer, Gujranwala Punjab Base, Ray Pharmaceuticals, Karachi, Pakistan. Teaching Experience: 8 years Total Working Experience: 10 years
•Member “Drug Delivery” Research Group, RIHMS, Department of Pharmaceutics, College of Pharmacy, University of Sharjah. •Member of Pakistan Pharmaceutical Association (MPPA), Pakistan, 2008 – To date. •Member (MyCRS00100) of “The Malaysia Local Chapter of The Controlled Release Society” March 2017 – March 2018. •Senior Advisor of “Initiator Pharmacist Federation (IPF)” – Malaysia Chapter, Pakistan, JAN 2015 – To date.
1. Hyaluronic Acid Functionalized Nanoparticles for Co-Delivery of Methotrexate and Zoledronic Acid: Fabrication, Characterization and in Vitro Evaluation Using RAW 264.7 and LNCaP Cells 2. PEGylated Polymeric Nanoparticles as Anticancer Drug Delivery System: Optimization, Stability and Interaction with Various Cancer Cells 3. Hyaluronic Acid Functionalized Polymeric Nanoparticles for Targeted delivery of Tamoxifen and Paclitaxel: Fabrication, Characterization and in Vitro Evaluation 4. Curcumin Based Strategies in Wound Healing and Repair: Nanomedicines are efficient macromolecules 5. Cell membrane cloaked nanomedicines for bio-imaging and immunotherapy of cancer: Evaluation of pharmacokinetics, cell internalization and anticancer efficacy
1. Zahid Hussain*, Muhammad Abdur Rahim, Nasrullah Jan, Hassan Shah, Mutasem Rawas-Qalaji, Shahzeb Khan, Mohammad Sohail, Hnin Ei Thu, Nor Amlizan Ramli, Rai Muhammad Sarfraz, Mohammed A.S. Abourehab. Cell membrane cloaked nanomedicines for bio-imaging and immunotherapy of cancer: Improved pharmacokinetics, cell internalization and anticancer efficacy. Journal of Controlled Release 2021, 335: 130-157 (I.F = 9.77, Q1). 2. Zahid Hussain*. Nanotechnology guided newer intervention for treatment of osteoporosis: efficient bone regeneration by up-regulation of proliferation, differentiation and mineralization of osteoblasts. International Journal of Polymeric Materials and Polymeric Biomaterials 2021; 70(1): 1-13 (I.F = 2.61, Q2). 3. Zahid Hussain, Hnin Ei Thu*, Ibrahim Elsayed, Shahzeb Khan, Mohammad Sohail, Muhammad Asim Farooq, Rai Muhammad Sarfraz. Nano-scaled materials may induce severe neurotoxicity upon chronic exposure to brain tissues: a critical appraisal and recent updates on predisposing factors, underlying mechanism and future prospects. Journal of Controlled Release 2020; 328: 873-894 (I.F = 9.77, Q1). 4. Zahid Hussain*, M. Pandey, H. Choudhury, P.C. Ying, T.M. Xian, T. Kaur, G.W. Jia, B. Gorain. Hyaluronic acid functionalized nanoparticles for simultaneous delivery of curcumin and resveratrol for management of chronic diabetic wounds: Fabrication, characterization, stability and in vitro release kinetics. Journal of Drug Delivery Science and Technology 2020, 57: 101747 (I.F = 3.98, Q2). 5. Fang G, Zhang Q, Pang Y, Thu HE, Zahid Hussain*. Nanomedicines for improved targetability to inflamed synovium for treatment of rheumatoid arthritis: Multi-functionalization as an emerging strategy to optimize therapeutic efficacy. Journal of Controlled Release 2019; 303:181-208 (I.F = 9.77, Q1). 6. Md S, Kuldeep Singh JKA, Waqas M, Pandey M, Choudhury H, Habib H, Hussain F, Zahid Hussain*. Nanoencapsulation of betamethasone valerate using high-pressure homogenization-solvent evaporation technique: optimization of formulation and process parameters for efficient dermal targeting. Drug Development and Industrial Pharmacy 2019; 45: 323-332 (I.F = 3.22, Q2). 7. Zahid Hussain*, Khan S, Imran M, Sohail M, Shah SWA, de Matas M. PEGylation: a promising strategy to overcome challenges to cancer-targeted nanomedicines: a review of challenges to clinical transition and promising resolution. Drug Delivery and Translational Research 2019; 9(3): 721–734 (IF = 4.62, Q1). 8. Gao X, Guo L, Li J, Thu HE, Zahid Hussain*. Nanomedicines guided nanoimaging probes and nanotherapeutics for early detection of lung cancer and abolishing pulmonary metastasis: Critical appraisal of newer developments and challenges to clinical transition. Journal of Controlled Release 2018; 292: 29-57 (I.F = 9.77, Q1). 9. Shahzeb Khan, Muhammad Imran, Tariq Tahir Butt, Syed Wadood Ali Shah, Muhammad Sohail, Arif Malik, Srijit Das, Hnin Ei Thu, Aishah Adam, Zahid Hussain*. Curcumin Based Nanomedicines as Efficient Nanoplatform for Treatment of Cancer: New Developments in Reversing Cancer Drug Resistance, Rapid Internalization, and Improved Anticancer Efficacy. Trends in Food Science and Technology 2018, 80, 8–22 (I.F = 12.56, Q1). 10. Fan Zhuo, Muhammad A.S. Abourehab, Zahid Hussain*. Hyaluronic Acid Decorated Tacrolimus-Loaded Nanoparticles: Efficient Approach to Maximize Dermal Targeting and Anti-dermatitis Efficacy. Carbohydrate Polymers 2018; 197: 478-489. (I.F = 9.38, Q1).
1. Hyaluronic Acid Functionalized Nanoparticles for Co-Delivery of Methotrexate and Zoledronic Acid: Fabrication, Characterization and in Vitro Evaluation Using RAW 264.7 and LNCaP Cells 2. PEGylated Polymeric Nanoparticles as Anticancer Drug Delivery System: Optimization, Stability and Interaction with Various Cancer Cells 3. Hyaluronic Acid Functionalized Polymeric Nanoparticles for Targeted delivery of Tamoxifen and Paclitaxel: Fabrication, Characterization and in Vitro Evaluation
1. Featured among Top 2% Scientists in the World based on Scopus Citation Index published by Standford University USA in 2020. 2. Outstanding Scientists Award 2020 in 9th International Scientist Awards on Engineering, Science, and Medicine, VDGOOD Technology Factory, Trichy, India – 12 & 13 September 2020 (Profile ID: VDSA2898). 3. Three (3) of my articles featured as the “Top Most Cited Articles” published in Drug Delivery Science and Technology (impact factor 4.62, Q1). 4. Gold Medal Award, Invention, Innovation, and Drug Exposition (IIDEX 2018), Universiti Teknologi MARA (UiTM), Malaysia. 5. Gold Medal Award, Invention, Innovation, and Drug Exposition (PHARMA-IIDEX 2018), Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Malaysia. 6. Bronz Medal Award, Invention, Innovation, and Drug Exposition (IIDEX 2017), Universiti Teknologi MARA (UiTM), Malaysia. 7. Excellence Award 2016, in recognition of excellent academic and research achievements, Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, Bandar Puncak Alam, Malaysia. 8. Best Lecturer Award 2016, Department of Pharmaceutics, Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, Bandar Puncak Alam, Malaysia 9. Best Poster Presentation award on 2nd International Conference of Advanced Medical Search (ICAMS) 2015, Concorde Hotel, Malaysia. 10. Research Fellowship award “The Research Universiti Malaysia Fellowship Scheme 2012” (Sep 2012 to June 2013), Universiti Kebangsaan Malaysia, Malaysia.
1. Associate Editor – Frontiers in Pharmacology: Experimental Pharmacology and Drug Discovery (https://www.frontiersin.org/my-frontiers/overview). 2. Editorial Board Member – International Journal of Pharmacy and Pharmaceutical Sciences (IJPPS) (https://innovareacademics.in/journals/index.php/ijpps/editorial-board). 3. Editorial Board Member – INNOSC Theranostics and Pharmacological Sciences. (http://journals.innosciencepress.com/index.php/ITPS/about/editorialTeam). 4. Official reviewers of more than 20 International high impact factor journals. 5. External examiner of Master and Ph.D. research thesis (National/International).
As a teacher, I strongly believe that learning needs to be student-centered and that students should be equal partners in the learning process. One of my ultimate objectives in teaching is to facilitate learning by helping my students to gain necessary skills to take control and become active participants in their own learning. I believe that teaching is the most significant role in a community, where we (teachers) healthily contribute in educating the generations to function knowledgeably in a society where rapid technological advances constantly pose new questions and ethical challenges. To achieve my objectives as an effective teacher, I let students to know that my role in the teaching/seminar hall is to be a facilitator, not a provider of information. I intend to create multiple discussion questions during my lecture session in order to engage my students and to stimulate motivation. I always provide detailed descriptions of writing assignments and I provide samples so that they are able to see what a good finished product should look like. Further, I share my analysis with the class as we end each module. Being a teacher, I also believe in fostering critical thinking skills to facilitate the acquisition of lifelong learning skills, to guide students in developing evidence-based problem-solving strategies and to prepare students to develop critical writing skills to get them prepared for post-grad studies/researches.
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