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Hamadeh Tarazi Academic RankLecturer
Hamadeh Tarazi

Specialization:

  • In-silico Drug Design

Research Interests:

  • Applying molecular modeling techniques in drug discovery, screening of structural databases against different macromolecular targets.

Contact

- M.Sc. Pharmaceutical Sciences (In-silico Drug Design), University of Jordan, 2003 - B.Sc. Pharmcy, Philadelphia University, 2001
- 2011-current Lecturer, University of Sharjah, College of Pharmacy, UAE. - 2009-2011 Lecturer, Salman Bin Abdel-Aziz University, College of Pharmacy, SA. - 2004-2009 Lecturer, Philadelphia University, Faculty of Pharmacy, Jordan. - 2001-2004 Lab. Supervisor, Philadelphia University, Faculty of Pharmacy, Jordan.
- Jordanian Pharmacists Association - Arab Union of Pharmacists
• Discovery of Novel Small-Molecule Inhibitors of SARS-CoV 2 Main Protease as Potential Leads for COVID-19 Treatment. Anjela Manandhar, Vunnam Srinivasulu, Mohamad Hamad, Hamadeh Tarazi, Hany Omar, Dennis J. Colussi, John Gordon, Wayne Childers, Michael L. Klein, Taleb H. Al-Tel, Magid Abou-Gharbia, and Khaled M. Elokely (2021). Journal of Chemical Information and Modeling: DOI 10.1021/acs.jcim.1c00684 • Current Status of Baricitinib as a Repurposed Therapy for COVID-19. Maha Saber-Ayad, Sarah Hammoudeh, Eman Abu-Gharbieh, Rifat Hamoudi, Hamadeh Tarazi, Taleb H. Al-Tel and Qutayba Hamid (2021). Pharmaceuticals: Vol. 14, Issue. 7, Article Number 680. • Discovery of first-in-class imidazothiazole-based potent and selective ErbB4 (HER4) kinase inhibitors. Seyed-Omar Zaraei, Rawan M. Sbenati, Nour N. Alach, Hanan S. Anbar, Randa El-Gamal, Hamadeh Tarazi, Mahmoud K. Shehata, Mohammed S. Abdel-Maksoud, Chang-Hyun Oh, Mohammed I. El-Gamal (2021). European Journal of Medicinal Chemistry: Vol. 224, Article number 113674. • Camel whey protein hydrolysates induced G2/M cellcycle arrest in human colorectal carcinoma. Chandraprabha Murali, Priti Mudgil, Chee‑Yuen Gan, Hamadeh Tarazi, Raafat El‑Awady, Youssef Abdalla, Amr Amin & Sajid Maqsood (2021). Scientific Reports: Vol. 11, Issue. 1, Article Number 7062. • Design, synthesis, biological evaluation, and modeling studies of novel conformationally-restricted analogues of sorafenib as selective kinase-inhibitory antiproliferative agents against hepatocellular carcinoma cells. Rawan M. Sbenati, Seyed-Omar Zaraei, Mohammed I. El-Gamal, Hanan S. Anbar, Hamadeh Tarazi, Malaka M. Zoghbor, Najma A. Mohamood, Mahta M. Khakpour, Dana M. Zaher, Hany A. Omar, Nour N. Alach, Mahmoud K. Shehata, Randa El-Gamal (2021). European Journal of Medicinal Chemistry: Vol. 210, Article number 113081. • Imidazothiazole-based potent inhibitors of V600E-B-RAF kinase with promising anti-melanoma activity: biological and computational studies. Hanan S. Anbar, Mohammed I. El-Gamal, Hamadeh Tarazi, Bong S. Lee, Hong R. Jeon, Dow Kwon, Chang-Hyun Oh (2020). Journal of Enzyme Inhibition and Medicinal Chemistry: Vol. 35, No. 1, Pages 1712-1726. • Possible metabolic conversion of pinene to ionone. Taleb H. Al-Tel, Hamadeh Tarazi, Lujain O. Aloum, Dietrich E. Lorke, Georg Petroianu (2020). Die Pharmazie: Vol. 75, Issue. 7, Pages 360-363. • Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids. Hajjaj H. M. Abdu-Allah, Alshaimaa A. B. Abdelmeoaz, Hamadeh Tarazi, Abdel-Nasser A. El-Shorbagi, Raafat El-Awady (2020). Bioorganic Chemistry: Vol. 94, Article number 103378. • Discovery of a potent p38α/MAPK14 kinase inhibitor: Synthesis,in-vitro/in-vivo biological evaluation, and docking studies. Mohammed I. El-Gamal, Hanan S. Anbar, Hamadeh Tarazi, Chang-Hyun Oh (2019). European Journal of Medicinal Chemistry: Vol. 183, Article number 111684. • Discovery of highly potent V600E-B-RAF kinase inhibitors: Molecular Modeling Study. Hamadeh Tarazi, Mohammed I. El-Gamal, Chang-Hyun Oh (2019). Bioorganic and Medicinal Chemistry: Vol. 27, Issue. 4, Pages 655-663.
• Design and synthesis of novel indole-based rigid analogues of Sorafenib as more selective kinase-inhibitory antiproliferative agents, Co-Supervision, (2020). • GC-MS based comparative metabolomics of MCF-7 breast cancer cells using different extraction solvents: Evidence of Warburg Effect, Co-Supervision, (2019) • Quantification of Thiamine and Nicotinamide in Multivitamin Preparations by Reversed Phase High Performance Liquid Chromatography (RP-HPLC): An Application of Method Validation According to the ICH Guidelines (2012). • Reversed-Phase High-Performance Liquid Chromatography (RP-HPLC) Analysis of Cefpodoxime Proxetil in Tablet Dosage Forms (2012).
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