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Prof.Abdel-Nasser Ahmed El-Shorbagi Academic RankProfessor

Specialization:

  • Medicinal Chemistry

Research Interests:

  • Drug Design and Discovery, Pharmacology and Pharmaceutical Sciences, Prodrugs and Targeted Drugs

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• B. Sc., Pharmaceutical Sciences 1979, Faculty of Pharmacy, Assiut University. • M.Sc., Pharmaceutical Sciences, Pharm Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt. • Ph. D. Med &Pharm Chemistry, 1989, Faculty of Pharmaceutical Sciences, Chiba University, Chiba, Japan, (Channel) with Assiut University
• Professor; Med Chemistry, Sept. 1, 2010, College of Pharmacy, University of Sharjah, Sharjah, UAE • Visiting Professor; Med Chemistry, Sept. 1, 2009-2010. • Professor; Med & Pharm Org Chemistry, Nov 2004-2008, Faculty of Pharmacy, Al-Isra University, Amman, Jordan. • Professor; Med &Pharm Chemistry, Nov 2000, Faculty of Pharmacy, Assiut University, Assiut, Egypt • Associate professor 1995-2000, Faculty of pharmaceutical sciences, university of Assiut, Assiut, Egypt. • Assistant professor 1989-1995, Faculty of pharmaceutical sciences, university of Assiut, Assiut, Egypt. • Research fellow for Ph.D. Chiba Univ, JAPAN. 1986-1989. • Lecturer; Pharm Chem 1984, Faculty of Pharmacy, Assiut University, Assiut, Egypt. • Assigned Demonstrator of pharmaceutical chemistry, Dept. Pharm Chem 1979, Faculty of Pharmacy, Assiut University, Assiut, Egypt. • B. Sc., Pharmaceutical Sciences 1974-1979. • Faculty of Pharmacy, Assiut University
• Member of Pharmacists Syndicate, Egypt • Member of the Medical Professions Syndicate, Egypt
• Design and Development of Safe and Selective Antibacterial Agents Against Multidrug Resistant Superbugs with financial support of a total sum of DHs 80,000 for 24 months, starting from February 21st, 2021 • Deanship of Scientific Research (DSR), King Abdulaziz University, Jeddah, under grant No. (D-200-166-1440). The authors, therefore, gratefully acknowledge the DSR technical and financial support.
• Marine Sponge is a Promising Natural Source of Anti-SARS-CoV-2 Scaffold. Hamoda, A. M., Fayed, B., Ashmawy, N. S., El-Shorbagi, A. N. A., Hamdy, R., & Soliman, S. S. M., Frontiers in Pharmacology, 2021, 12. https://doi.org/10.3389/fphar.2021.666664 • A sensitive liquid chromatography-tandem mass spectrometric method for determination of five β-blockers after labeling with either hydrazonoyl chloride or dansyl chloride reagent, Khedr A, Khayyat AN, El-Shorbagi AN, Kammoun AK., Journal of Chromatography B. 2020 Dec 1;1160:122383., https://doi.org/10.1016/j.jchromb.2020.122383 , PMID: 32949926 • Induction of DNA damage, apoptosis and cell cycle perturbation mediate cytotoxic activity of new 5-aminosalicylate–4-thiazolinone hybrid derivatives, Ramadan WS, Saleh EM, Menon V, Vazhappilly CG, Abdu-Allah HH, El-Shorbagi AN, Mansour W, El-Awady R., Biomedicine & Pharmacotherapy. 2020 Nov 1;131:110571., https://doi.org/10.1016/j.biopha.2020.110571 • A comprehensive review on management of Parkinson’s disease, inclusive of drug discovery and pharmacological approaches, El-Shorbagi AN, Chaudhary S, Alshemali KA, Alabdulrazzaq RF, Alqahtani FY., Journal of Applied Pharmaceutical Science. 2020 Oct;10(10):130-150. https://doi.org/ 10.7324/JAPS.2020.1010015 • Liquid chromatography-diode array-mass spectrometric analysis of amino and mercapto compounds coupled with chloroimino derivatization reagent, Khedr A, Khayyat AN, El-Shorbagi AA., Journal of Chromatography A. 2020 Apr 17:461078. • Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids, Abdu-Allah H, A. B. Abdelmeoaz A, Tarazi H, El-Shorbagi A-NA, El-Awady R., Bioorganic Chemistry. 2019:103378. https://doi.org/10.1016/j.bioorg.2019.103378 • Sachin Chaudhary, Ramesh Kumar Gupta, Mandeep Kumar Gupta, Harish Chandra Verma, Hitesh Kumar, Amit Kumar, Sudhansu Ranjan Swain, Abdel-Nasser El-Shorbagi, Hepatoprotective response of Cordia sebestena L. fruit against simvastatin induced hepatotoxicity, Journal of Pharmacy & Pharmacognosy Research, 8, (4), 327-335. • Sameh Soliman, Alshaimaa M. Hamoda, Abdel-Nasser A. El-Shorbagi, Ali A. El-Keblawy, Novel Betulin Derivative is Responsible for the Anticancer Folk Use of Ziziphus spina-christi from the Hot Environmental Habitat of UAE, Journal of Ethnopharmacology, 2019, 231, 403-408 https://doi.org/10.1016/j.jep.2018.11.040. • Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types, Vazhappilly, C. G.; Saleh, E.; Ramadan, W.; Menon, V.; Al-Azawi, A. M.; Tarazi, H.; Abdu-Allah, H.; El-Shorbagi, A.-N.; El-Awady, R., Investigational New Drugs 2019, 37 (2), 252-261. https://doi.org/10.1007/s10637-018-0626-5 • 10- Monobactams: A Unique Natural Scaffold of Four-Membered Ring Skeleton, Recent Development to Clinically Overcome Infections by Multidrug- Resistant Microbes, Abdel Nasser E-S, Sachin C., Letters in Drug Design and Discovery. 2019; 16 (12): 1305-20. https://doi.org/10.2174/1570180816666190516113202
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