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Dr. Maha Mohamed Saber Khalil Ayad Clinical Sciences Department Academic RankAssociate Professor

Specialization:

  • Pharmacology

Research Interests:

  • Pharmacogenetics, Clinical Pharmacology, Cardiovascular Pharmacology, Cancer Research

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MBBS (1995) MSc (pharm), 2001 MRCP(UK), 2003 MD (PhD equiv. pharm), 2006 FRCP(Edinburgh), 2013 MSc (Leadership in Health Profession Education, RCSI), 2015
2015-Current Associate Professor of Pharmacology, Faculty of Medicine, Cairo University. 2009-2015 Assistant Professor of Pharmacology, College of Pharmacy, University of Sharjah, UAE 2004- 2010 Tutor in the Egyptian Medical Syndicate preparatory courses for MRCP(UK). 2008- 2009 Member of the Committee of Clinical Pharmacology & Pharmacy, Cairo University Hospitals. 2006- Jan, 2009 Clinical and genetic consultant of Bibliotheca alexandrina Hypertrophic Cardiomyopathy (BA-HCM) research project in Cairo (the project is under support of MagdiYacoub Research Institute in Harefield and Oxford University- UK). 2001-2004 Assistant Lecturer of Pharmacology, Faculty of Medicine, Cairo University. 1999-2001 Demonstrator of Pharmacology, Cairo University 1997-1999 Full-time Resident, Critical Care Department, Kasr Al-Aini University Hospitals, Faculty of Medicine, Cairo University. 1996-1997 House Officer, Kasr Al-Aini University Hospitals, Faculty of Medicine, Cairo University.
Member of the editorial board of : Journal of Pharmaceutics and Pharmacology • Reviewer in: 1. Journal of Renin-Angiotensin Aldosterone System 2. Cell Biochemistry and Biophysics 3. Clinical Medicine and Diagnostics 4. Journal of Mood Disorders 5. Journal on Complementary Medicine and Drug Discovery
ellowship of the Royal College of Physician, Edinburgh, UK • Member of the British Pharmacology Society • Membership of the International Menopause Society • Membership of the Emirati Medical Society
• Mechanism of action of new imidazopyridine derivatives in breast and lung cancers”, seed grant (2011-2013). • Prevalence of statin-induced myopathy SLCO 1B1 gene polymorphism in UAE population, supported by the College of Research, UoS, (collaborative grant, Current)
Johnson JN, Grifoni C, Bos JM, Saber-Ayad M,Ommen SR, Nistri S, Cecchi F, Olivotto I, Ackerman MJ. Prevalence and clinical correlates of QT prolongation in patients with hypertrophic cardiomyopathy. Eur Heart J. 2011 May;32(9):1114-20. 2. Saber-Ayad M,Nassar YS, Latif IA. Angiotensin-converting enzyme I/D gene polymorphism affects early cardiac response to professional training in young footballers. JRAAS 2014;15(3): 236-42. 3. Ibrahim OM, Saber-Ayad M. Antibiotic misuse in different hospital wards (A pilot study in an Egyptian Hospital). AJPCR 2012;5(2):95-7. 4. Semreen MH, EL-Awady R, Abu-Odeh R, Saber-Ayad M, Al-Qawasmeh R, Chouaib S, Voelter W, Al-Tel T. Tandem Multicomponent Reactions toward the design and synthesis of novel antibacterial and cytotoxic motifs. Curr Med Chemistry 2013;20: 1445-59. 5. KassemHSh, Azer RS, Ayad MS,Moharem-Elgamal S, Magdy G, Elguindy A, Cecchi F, Olivottol I, Yacoub MH. Early reaults of sarcomeric gene screening from the Egyptian National BA-HCM Program. JCATR 2013; 6(1):65-80. 6. Mostafa-Hedeab G, Saber-Ayad M,Latif IA, Elkashab SO, AbdElshafey S, Elshaboney TH, Mostafa MI, Zaki MM.Functional G1199A ABCB1 polymorphism may have an effect on cyclosporine blood concentration in renal transplanted patients. J clin Pharmacol 2013; 53(8):827-33. 7. Omar HA, Tolba MF, Saber-Ayad M. Potential Targets of Energy Restriction Mimetic Agents in Cancer Cells. Future Oncology 2014; 10(16):2547-2550. 8. El-Awady R, Semreen MH, Saber-Ayad M, Cyprian F, Menon V, Al-Tel T. Modulation of DNA damage response and induction of apoptosis mediates synergism between doxorubicin and a new imidazopyridine derivative in breast and lung cancer cells. DNA Repair 2016;37: 1-11
unction G1199 ABCB1 polymorphism may have an effect on cyclosporine blood concentration in renal transplanted patients (MD thesis, 2011). • Prevalence of FTO obesity gene polymorphisms in UAE population, funded by Boehringer Ingelheim research grants (current). • Effect of Galanin expression on caspase 8 –mediated apoptosis and sensitivity to chemotherapy in colorectal cancer, funded by Boehringer Ingelheim research grants (current).
First Award for Young Investigators in the Annual International Conference of the Egyptian Society of Cardiology, February, 2002. o Third Young Investigator's Award in the 6th Annual Meeting of the Egyptian Society of Hypertension, April, 2002. o First Young Investigator's Award in the 10th Annual Meeting of the Egyptian Society of Hypertension, April, 2006. o Award for the best thesis, Cairo University, 2009 (as a supervisor). o Award for best research group, University of Sharjah, 2011/2012.
a. Sharjah Radio interview on “Hormonal replacement therapy” b .TV interview on “Addiction” c. Collaboration in the project of “Read for blind” in Emeriti Society for Blind
I consider teaching one of the most interesting jobs. I’ve been teaching Pharmacology since 1999. My ultimate goal is to help student getting the passion for learning. They should get the knowledge, skills and attitude that enable them to satisfy the patient’s needs. In addition, they should develop research skills. With the rapidly evolving knowledge in every and each branch of science, students should have enough curiosity to become a life-long learners. My main task in all courses is to foster critical thinking and to encourage involvement of the students in objective discussion. Problem solving is usually more interesting for the students and more close to real life and what is expected in their practice in the future. I try to focus on discussing basic as well as practical issues in depth, rather than flooding them with unnecessary peripheral information; quality of information is much more important. Developing a good relationship among patients and members of the health team is one of the major goals I am trying to emphasize all through my courses for future physicians, pharmacists and dentists. Being knowledgeable and mastering communication skills provide the students with the confident attitude required in their practice
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