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Prof.Yasser Khalil Bustanji Department of Basic Medical Science Academic RankProfessor

Specialization:

  • Biochemistry

Research Interests:

  • My research interests include various research lines of research as: Clinical biochemistry research, biomarkers, identification and testing of novel compounds and medicinal plants as potential candidates for development of new pharmaceutical drugs, cytotoxicity studies and cancer researches, and nanotechnology research.

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Ph.D in Biochemistry
Sep 2021 –current Professor, Department of Basic Medical Sciences, University of Sharjah April 2002- current Faculty member / Department of Biopharmaceutics and Clinical Pharmacy/ Faculty of Pharmacy, University of Jordan Sep 2016- Dec 2019 Director of Hamdi Mango Center for Scientific research, University of Jordan Aug 2011-2013 Deputy Dean, Faculty of Pharmacy, University of Jordan Nov 2010 - 2011 Chairman, Department of Biopharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, Jordan University, Amman Jordan. Sep 2007- Sep 2008 Associate Professor, Faculty of Pharmacy, Applied Science University
2010- Current Consultant with Accreditation and Quality assurance Commission of Higher education Institutions. 2010-2018 Consultant with the Jordan Food and Drug Administration GMP Inspection teams. 2011 – 2021 Member in Intel International Science and Engineering Fair evaluation committee
1996-current. Jordan Pharmaceutical Association (Jordan). 2008 – 2013 Member of the Bioequivalence and Biowaiver Committee, Jordan Food and Drug Administration (JFDA), Amman, Jordan. 2008 – Current Member in Jordan National Centre of Biotechnology 2011 – 2021 Member in Intel International Science and Engineering Fair evaluation committee
1. Eman Y. Abu-rish, Yasser Bustanji and Kamel Abusal. Nationwide Routine Childhood Vaccination Coverage During the COVID-19 Pandemic in Jordan: Current Situation, Reasons, and Predictors of Vaccination. International Journal of Clinical Practice, Volume 2022 |Article ID 7918604 | https://doi.org/10.1155/2022/7918604 2. Jehad Almaliti, Muhammed Alzweiri, Momen Alhindy, Tamam Al-Helo, Ibrahim Daoud, Raghad Deknash, C. Benjamin Naman , Bashaer Abu-Irmaileh, Yasser Bustanji and Islam Hamad. Discovery of Novel Epoxyketone Peptides as Lipase Inhibitors. Molecules 2022, 27, 2261. 3. Waseem El-Huneidi, Shabana Anjum, Mohamed A. Saleh, Yasser Bustanji, Eman Abu-Gharbieh and Jalal Taneera. Carnosic Acid Protects INS-1 -Cells against Streptozotocin-Induced Damage by Inhibiting Apoptosis and Improving Insulin Secretion and Glucose Uptake. Molecules 2022, 27, 2102 4. Yasser Bustanji, Noor Barham, Eman Y. Abu-rish, Abdelkarim Hiari,… Hana Bajes. .. Evaluation of Lipoprotein (A) Levels in Type 2 Diabetic Jordanian Patients. Hormone Molecular Biology and Clinical Investigation. 2022 Apr 15. doi: 10.1515/hmbci-2021-0090. 5. Bajes, H.R., Oran, S.A., Yasser Bustanji. Chemical Composition and Antiproliferative and Antioxidant Activities of Essential Oil from Juniperus phoenicea L. Cupressaceae. Research Journal of Pharmacy and Technology, 2022, 15(1), pp. 153–159 6. Sara Khaleel, Yusuf Al-Hiari, Violet Kasabri, Randa Haddadin, Rabab Albashiti, Muhammad Al-Zweri, Yasser Bustanji. Antiproliferative properties of 7, 8-Ethylene Diamine Chelator-Lipophilic Fluoroquinolone Derivatives Against colorectal cancer Cell Lines. Anti-Cancer Agents in Medicinal Chemistry, 2022, 22(5), pp. 1012–1028 7. Arwa R. Althaher, Sawsan A. Oran, Yasser K. Bustanji. Induction of apoptosis by Ruta chalepensis L. essential oil in human breast cancer cells (MCF-7). Journal of Pharmacy & Pharmacognosy Research 2022, 10 (1), 73-83 8. Zaynab Al-Eisawi, Salim M. Abderrahman, Islam F. Al-khalaf, Reem Al-Abbassi, Yasser K. Bustanji. Taraxacum Officinale Extracts Exhibit Safe and Selective Anticancer Activity. The Natural Products Journal 2022, 12, Article ID: e160921187741. DOI: 10.2174/2210315510999201109202255 9. Lobna Gharaibeh, Walhan Alshaer, Suha Wehaibi, Rula Al Buqain, Dana A Alqudah, Abdulfattah Al-Kadash, Hafsa Al-Azzawi, Abdalla Awidi, Yasser Bustanji. Fabrication of aptamer-guided siRNA loaded lipopolyplexes for gene silencing of notch 1 in MDA-mb-231 triple negative breast cancer cell line. Journal of Drug Delivery Science and Technology, 2021, 65, 102733 10. Lama Hamadneh, Bashaer Abu-Irmaileh, May Al-Majawleh, Yasser Bustanji, Yazun Jarrar, Tariq Al-Qirim. Doxorubicin–paclitaxel sequential treatment: insights of DNA methylation and gene expression changes of luminal A and triple negative breast cancer cell lines. Molecular and Cellular Biochemistry, 2021, 476(10), pp. 3647–3654. 11. Lafi, Z., Alshaer, W., Hatmal, M.M., Zihlif, M., Alqudah, D.A., Nsairat, H., Azzam, H., Aburjai, T., Bustanji, Y., Awidi, A. Aptamer-functionalized pH-sensitive liposomes for a selective delivery of echinomycin into cancer cells. RSC Advances, 2021, 11(47), pp. 29164–29177 12. Hala I. Al-Daghistani, Lubna F. Abu-Niaaj, Yasser Bustanji, Khawla D. Al-Hamaideh, Husam Al-Salamat, Moayyad N. Nassar, Hatim M. Jaber, Nabil H. Amer, Bashaer Abu-Irmaileh, Abdulameer Al-Nuaimi. Antibacterial and Cytotoxicity Evaluation of Arum hygrophilum Bioss. European Review for Medical and Pharmacological Sciences, 2021, 25(23), pp. 7306–7316 13. Bajes, H.R., Oran, S.A., Bustanji, Y.K. Chemical Composition and Antiproliferative and Antioxidant Activities of Methanolic Extract of Alcea setosa A. Malvaceae. Research Journal of Pharmacy and Technology, 2021, 14(12), pp. 6447–6454 14. Nassim Belkacem, Bachra Khettal, Mohammad Hudaib, Yasser Bustanji, Bashaer Abu-Irmaileh, Chiraz Soumia M Amrine. Antioxidant, antibacterial, and cytotoxic activities of Cedrus atlantica organic extracts and essential oil. European Journal of Integrative Medicine, 2021, 42, 101292 15. Amer Imraish, Tuqa Abu Thiab, Wajdy Al‐Awaida, Hamzeh J. Al‐Ameer, Yasser Bustanji, Hana Hammad, Mays Alshari, Afnan Al‐Hunaiti. In vitro anti‐inflammatory and antioxidant activities of ZnFe2O4 and CrFe2O4 nanoparticles synthesized using Boswelliacarteri resin. Journal of Food Biochemsitry. Journal of Food Biochemistry, 2021, 45(6), e13730. 16. Sayed, U., Hudaib, M., Issa, A., Tawaha, K., Bustanji, Y. Plant products and their inhibitory activity against xanthine oxidase. Farmacia, 2021, 69(6), pp. 1042–1052 17. Althaher, A.R., Oran, S.A., Bustanji, Y.K. Chemical composition, in vitro evaluation of antioxidant properties and cytotoxic activity of the essential oil from calamintha incana (Sm.) helder (lamiaceae). Tropical Journal of Natural Product Research, 2021, 5(8), pp. 1333–1339 18. Almasri, I., Othman, H., Abu-Irmaileh, B., Moham-Mad, M., Bustanji, Y. Flavonoids from plant source as protein tyrosine phosphatase 1b inhibitors: In silico update. Acta Pharmaceutica Sciencia, 2021, 59(4), pp. 619–640 19. Israa Yousef, Sawsan Oran, Moath Alqaraleh, Yasser Bustanji. Evaluation of Cytotoxic, Antioxidant and Antibacterial Activities of Origanum dayi, Salvia palaestina and Bongardia chrysogonum Plants Growing Wild in Jordan. Tropical Journal of Natural Product Research. 2021, 5 (1), 66- 70 20. Abeer Khriesha, Yasser Bustanji, Rana Abu Farha, Reem Al-Abbasi, Bashaer Abu-Irmaileh Evaluation of the potential anticancer activity of different vitamin D metabolites on colorectal and breast cancer cell lines. Hormone Molecular Biology and Clinical Investigation. 2021, 1;42(1):3-9. 21. Iman Y Abu-rish, Ahmad T Mansour, Hebah T Mansour, Lina A Dahabiyeh, Shereen M Aleidi, Yasser Bustanji. Pregabalin inhibits in vivo and in vitro cytokine secretion and attenuates spleen inflammation in Lipopolysaccharide/Concanavalin A-induced murine models of inflammation. Scientific Reports 2020, 10 (1), 1-11 22. Violet Kasabri, Shereen Arabiyat, Yusuf Al-Hiari, Hiba Zalloum, Jehad Almaliti, Ahmad Telfah, Yasser K. Bustanji, Sundus Alalawi. Fluoroquinolones as a potentially novel class of antidiabesity and antiproliferative compounds: synthesis and docking studies. Canadian Journal of Chemistry. 2020, 98 (10), 635-645. 23. A Qasem, V Kasabri, E AbuRish, Y Bustanji, Y Al-Hiari, R AlAbbasi, B AbuRmilha, S Alalawi. Evaluation OF Potential Cytotoxic Effect of Different Proton Pump Inhibitors on Different Human Cancer Cell Lines. Anti-cancer agents in medicinal chemistry 2020, 20, 245-253.
1. Leen Oyoun Alsoud .Metabolomics and Proteomics Based Discovery of Novel Biomarkers for Diabetes in Metabolic Syndrome Patients Assessed by Liquid Chromatography Ion Mobility-Mass Spectrometry-TOF (LC-TIMS-TOF). MSc Pharmaceutical sciences. Faculty of Pharmacy, UOS. (Co-supervisor). 2. Haneen I. Abufares A non-targeted multi-omics comparative study on COVID-19 vaccines Pfizer and Sinopharm, assed by (TIMS-QTOF) mass spectrometry . MSc Pharmaceutical sciences. Faculty of Pharmacy, UOS. (Co-supervisor). 3. Noor Tarawnah. The potential effect of scutellarein and berberine on the role of aquaporins 1,3, and 5 in invasion and metastasis of HT-29, SW-480 and HCT116 human colon cancer cell lines. Ph.D in Biological Sciences . Faculty of Science / University of Jordan, In progress research. 4. Elham Abusharaea. Epigenomic and transcriptomic changes in glioblastoma multiform cancer stem cells of U-87 cell line Ph.D in Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, 2022 5. Seham Ghannam. Invading cancer cells with quercetin using nanotechnology (in vitro by multi walled carbon nanotubes. M.Sc. in Clinical Pharmacy, Faculty of Pharmacy / University of Jordan. 2022 6. Hadeel AlHusaein. Chitosan Functionalized Multi-Walled Carbon Nanotubes as Nanocarriers for Delivery of Berberine in Cancer Cells. M.Sc. in Clinical Pharmacy, Faculty of Pharmacy / University of Jordan. 2022 7. AR Althaher. Phytochemical Analysis, In vitro Assessment of Antioxidant Properties and Cytotoxic Potential of of some medicinal plants. Ph.D in Biological Sciences . Faculty of Science / University of Jordan, 2020 8. Hana Bajes. The Potential Proliferative, Apoptotic, and Antioxidant Activities of Essential Oils of Thymus capitatus ( L.) Hoffmanns. & Link, Juniperus phoenicea L., Lonicera etrusca Santi., and Alcea setosa (Boiss.) Alef. on Human Breast and Colon Cancer Cell Lines and Normal Human Fibroblasts. Ph.D in Biological Sciences . Faculty of Science / University of Jordan, 2020
1. Ali Mango Prize for Distinguished Researcher for the Academic Year 2014 2. Distinguished Researchers Distinguished Researchers (highly cited Researchers) in the University of Jordan. 2019 3. Distinguished Researchers Distinguished Researchers (highly cited Researchers) in the University of Jordan. 2018 4. AL-Najah University Research Award for the year 2009 for the paper entitled: "Combining Ligand-Based Pharmacophore Modeling, QSAR Analysis and In -Silico Screening for the Discovery of New Potent Hormone Sensitive Lipase Inhibitors
1. Conducting Clinical/Nonclinical Expert Reports for pharmaceutical companies. 2. Conducting of Acute Oral and Topical Toxicity Studies 3. Conducting in Vivo Repeated Dose 28-Day Oral Toxicity studies
1. I believe that all students aim learn and it is my responsibility to facilitate and foster them to get their aims 2. I believe that all students have talents, interests and abilities unique only to them. It is my responsibility to provide them with an education that is appropriate for them as an individual 3. I believe that all students have to get their rights and opportunities regardless their ethnicity, religion sex and believes
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