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Dr.Firdos Ahmad Department of Basic Medical Science Academic RankAssistant Professor

Specialization:

  • Genetics, Thrombosis and Hemostasis, Heart Failure

Research Interests:

  • Genetics and Cardiovascular diseases

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•Ph.D. (Clinical Genetics, Hematology)Aug 2009 All India Institute of Medical Sciences, New Delhi, India •MSc. (Toxicology)May 2004 Hamdard University, New Delhi, India •BSc. (Biology, Chemistry) May 2000 University of Lucknow, Lucknow, India
Assistant Professor 2017-present College of Medicine, University of Sharjah, Sharjah, UAE Assistant Professor 2014- 2016 Division of Cardiovascular Medicine, Vanderbilt University, Nashville, TN, USA Post-Doctoral Fellows 2012- 2014 Center for Translational Medicine, Temple University, Philadelphia, PA, USA Post-Doctoral Fellow 2009- 2012 Department of Medicine, Thomas Jefferson University, Philadelphia, PA, USA Prof. Gunther Landbeck Fellow2007- 2008 University Medical Center Eppendorf, Hamburg, Germany
Ad-hoc Reviewer in Journals: Circulation, Hematology, Circulation Research, PLOS One, J. Am Heart Association’ Molecular and Cellular Biochemistry, DNA and Cell Biology, Journal of Pharmacy and Pharmacology
1. American Heart Association (AHA) 2012- 2017 2. International Society for Heart Research (ISHR) 2011- 2017 3. American Society of Hematology (ASH) 2010- 2011
1. Ahmad F, Singh AP, Tomar D, Rahmani M, Zhang Q, Woodgett JR, Tilley DG, Lal H, Force T. Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overload. J Mol Cell Cardiol. 2019 Mar 27;130:65-75. 2. Ahmad F, Kannan M, Obser T, Budde U, Schneppenheim S, Saxena R, Schneppenheim R. Characterization of VWF gene conversions causing von Willebrand disease. Br J Haematol. 2019 Mar;184(5):817-825. 3. Ahmad F. Vaccination: a novel potential therapeutic approach to limit thrombosis. J Am Heart Assoc. 2018 Jun 23;7(13). pii: e009861 4. Gupta M, Lal H Ahmad F, Sawyer DB, Hill MF. Chronic Neuregulin-1Β Treatment Mitigates the Progression of Post-Myocardial Infarction Heart Failure in the Setting of Type 1 Diabetes Mellitus by Suppressing Myocardial Apoptosis, Fibrosis and Key Oxidant-Producing Enzymes. J Card Fail. 2017: S1071-9164(17)31159-4. 5. Zhou J*, Ahmad F*, Parikh S, Hoffman NE, Rajan S, Verma VK, Song J, Yuan A, Shanmughapriya S, Guo Y, Gao E, Koch W, Woodgett JR, Madesh M, Kishore R, Lal H, Force T. Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy. Circ Res 2016: 118;1208-1222. 6. Ahmad F, Lal H, Zhou J, Vagnozzi RJ, Yu JE, Shang X, Woodgett JR, Gao E, Force T. Cardiomyocyte specific deletion of Gsk3 mitigates post-myocardial infarction remodeling, contractile dysfunction, and heart failure. J Am Col Cardiol 2014;64(7):696-706. 7. Lal H*, Ahmad F*, Zhou J, Yu JE, Vagnozzi RJ, Guo Y, Yu D, Tsai JE, Woodgett JR, Gao E, Force T. Cardiac fibroblast GSK-3β regulates ventricular remodeling and dysfunction in ischemic heart. Circulation 2014;130(5)419-30. 8. Zhou J, Freeman TA, Ahmad F, Shang X, Mangano E, Gao E, Farber J, Wang Y,Ma X, Woodgett J, Vagnozzi RJ, Lal H, Force T. GSK-3α is a central regulator of age-related pathologies in mice. J Clin. Invest 2013;123(4);1821-1832. 9. Edelstein L, Luna E, Gibson I, Bray M, Jin Y, Kondkar I, Nagalla S, Smith T, Hadjout-Rabi N, Covarrubias D, Jones SN, Ahmad F, Stolla M, Kong X, Dong J, Bergmeier W, Shaw C, Leal S and Bray PF. Human Genome-Wide Association and Mouse Knockout Approaches Identify Platelet Supervillin as an Inhibitor of Thrombus Formation under Shear Stress. Circulation 2012;25(72):2762-71. 10. Lal H, Zhou J, Ahmad F, Zaka R, Vagnozzi RJ, DeCaul M, Woodgett J, Gao E, Force T. GSK-3α Limits Ischemic Injury, Cardiac Rupture, Post- Myocardial Infarction Remodeling and Death. Circulation 2012;125(1):65-75 11. Ahmad F, Budde U, Jan R, Oyen F, Kannan M, Saxena R, Schneppenheim R. Phenotypic and molecular characterisation of type 3 von Willebrand disease in a cohort of Indian patients. Thromb Haemost 2013;109(4);652-660 12. Ahmad F, Jan R, Kannan M, Obser T, Hassan MI, Oyen F, Budde U, Saxena R, Schneppenheim R. Characterisation of mutations and molecular studies of type 2 von Willebrand disease. Thromb Haemost 2013;109(1):39-46 13. Ahmad F, Ouellette TD, Greene T, Poncz M, Feske S, Bergmeier W. Relative contribution of STIM1 and CalDAG-GEFI to calcium-dependent platelet activation and thrombosis. J Thromb Haemost. 2011;9(10):2077-86.
1. Pier M. Mannucci Young Investigator award – Editorial board of Journal of Thrombosis Haemostasis (2012) 2. U.S. New Investigator Travel Award from Boston ISTH Committee (conference not attended) (2011) 3. Travel Award from American Society of Hematology (ASH) committee Orlando Florida (2010) 4. Developing World Scientist award by 22nd International Society of Thrombosis and Hemostasis (ISTH) committee, (2009) 5. Reach the world Young Scientist award by 54th Standardization Committee (SSC) of ISTH, Vienna, Austria(2008)
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