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Dr.Firdos Ahmad Department of Basic Medical Science Academic RankAssociate Professor
Firdos Ahmad

Specialization:

  • Genetics, Thrombosis and Hemostasis, Ischemic and hypertensive cardiac diseases

Research Interests:

  • Genetic diseases, Cell signaling, Cardiomyopathy, Cardiac remodeling

Contact

Ph.D. (Clinical Genetics, Hematology) 2009 All India Institute of Medical Sciences, New Delhi, India MSc. (Toxicology) 2004 Hamdard University, New Delhi, India BSc. (Biology, Chemistry) 2000 University of Lucknow, Lucknow, India
Associate Professor 2021-Present College of Medicine, University of Sharjah, Sharjah, UAE Assistant Professor 2017-2021 College of Medicine, University of Sharjah, Sharjah, UAE Assistant Professor 2014- 2016 Division of Cardiovascular Medicine, Vanderbilt University, Nashville, TN, USA Post-Doctoral Fellows 2012- 2014 Center for Translational Medicine, Temple University, Philadelphia, PA, USA Post-Doctoral Fellow 2009- 2012 Department of Medicine, Thomas Jefferson University, Philadelphia, PA, USA Senior Research Fellow 2008- 2009 All India Institute of Medical Sciences (AIIMS), New Delhi, India Visiting Scientist (Prof. Gunther Landbeck Fellow) 2007- 2008 University Medical Center Eppendorf, Hamburg, Germany Junior Research Fellow 2004- 2007 All India Institute of Medical Sciences (AIIMS), New Delhi, India
Ad-hoc Reviewer in Journals: Circulation, Hematology, Circulation Research, European Heart Journal, J. Am Heart Association, Molecular and Cellular Biochemistry, Frontiers in Pharmacology, Bioengineered. Member of University & College Committees: a. Animal Care and Use Committee, University of Sharjah (2017- Present) b. College Research Committee (2017- Present) c. College Curriculum committee (2019-2021) d. College Program Evaluation & Educational Quality Assurance & Accreditation (2022- Present)
1. American Heart Association (AHA) 2. European Society of Cardiology (ESC) 3. American Society of Hematology (ASH)
1. Shahzadi SK, Marzook H, Qaisar R, Ahmad F. Nicotinamide riboside kinase-2 inhibits JNK pathway and limits dilated cardiomyopathy in mice with chronic pressure overload Clin Sci (Lond). 2022 Jan 28;136(2):181-196. 2. Yusuf AM, Qaisar R, Al-Tamimi AO, Jayakumar MN, Woodgett JR, Koch WJ, Ahmad F. Cardiomyocyte-GSK-3β deficiency induces cardiac progenitor cell proliferation in the ischemic heart through paracrine mechanisms. J Cell Physiol. 2021 Nov 23. doi: 10.1002/jcp.30644. 3. Ahmad F, Tomar D, Aryal A C S, Elmoselhi AB, Thomas M, Elrod JW, Tilley DG, Force T. Nicotinamide riboside kinase-2 alleviates ischemia-induced heart failure through P38 signaling. Biochim Biophys Acta Mol Basis Dis. 2020; 1866(3):165609 4. Ahmad F, Singh AP, Tomar D, Rahmani M, Zhang Q, Woodgett JR, Tilley DG, Lal H, Force T. Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overload. J Mol Cell Cardiol. 2019 Mar 27;130:65-75. 5. Ahmad F, Kannan M, Obser T, Budde U, Schneppenheim S, Saxena R, Schneppenheim R. Characterization of VWF gene conversions causing von Willebrand disease. Br J Haematol. 2019 Mar;184(5):817-825. 6. Zhou J*, Ahmad F*, Parikh S, Hoffman NE, Rajan S, Verma VK, Song J, Yuan A, Shanmughapriya S, Guo Y, Gao E, Koch W, Woodgett JR, Madesh M, Kishore R, Lal H, Force T. Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy. Circ Res 2016: 118;1208-1222. 7. Ahmad F, Lal H, Zhou J, Vagnozzi RJ, Yu JE, Shang X, Woodgett JR, Gao E, Force T. Cardiomyocyte specific deletion of Gsk3 mitigates post-myocardial infarction remodeling, contractile dysfunction, and heart failure. J Am Col Cardiol 2014;64(7):696-706. 8. Lal H*, Ahmad F*, Zhou J, Yu JE, Vagnozzi RJ, Guo Y, Yu D, Tsai JE, Woodgett JR, Gao E, Force T. Cardiac fibroblast GSK-3β regulates ventricular remodeling and dysfunction in ischemic heart. Circulation 2014;130(5)419-30. 9. Zhou J, Freeman TA, Ahmad F, Shang X, Mangano E, Gao E, Farber J, Wang Y,Ma X, Woodgett J, Vagnozzi RJ, Lal H, Force T. GSK-3α is a central regulator of age-related pathologies in mice. J Clin. Invest 2013;123(4);1821-1832. 10. Edelstein L, Luna E, Gibson I, Bray M, Jin Y, Kondkar I, Nagalla S, Smith T, Hadjout-Rabi N, Covarrubias D, Jones SN, Ahmad F, Stolla M, Kong X, Dong J, Bergmeier W, Shaw C, Leal S and Bray PF. Human Genome-Wide Association and Mouse Knockout Approaches Identify Platelet Supervillin as an Inhibitor of Thrombus Formation under Shear Stress. Circulation 2012;25(72):2762-71. 11. Lal H, Zhou J, Ahmad F, Zaka R, Vagnozzi RJ, DeCaul M, Woodgett J, Gao E, Force T. GSK-3α Limits Ischemic Injury, Cardiac Rupture, Post- Myocardial Infarction Remodeling and Death. Circulation 2012;125(1):65-75 12. Ahmad F, Ouellette TD, Greene T, Poncz M, Feske S, Bergmeier W. Relative contribution of STIM1 and CalDAG-GEFI to calcium-dependent platelet activation and thrombosis. J Thromb Haemost. 2011;9(10):2077-86. Full list of publication: https://www.ncbi.nlm.nih.gov/myncbi/1ryCmcu6xBH5U/bibliography/public/
1. Paul Dudley White International Scholar award - BCVS Scientific Session, American Heart Association (2021) 2. Pier M. Mannucci Young Investigator award – Editorial board of Journal of Thrombosis Haemostasis (2012) 3. U.S. New Investigator Travel Award from International Society of Thrombosis and Hemostasis (ISTH) Committee, Kyoto, Japan (conference not attended) (2011) 4. Travel Award from American Society of Hematology (ASH) committee Orlando Florida, USA (2010) 5. Developing World Scientist award by 22nd International Society of Thrombosis and Hemostasis (ISTH) committee, Boston, USA (2009) 6. Reach the world Young Scientist award by 54th Standardization Committee (SSC) of ISTH, Vienna, Austria (2008)
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