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Dr.Jalal Taneera Department of Basic Medical Sciences Academic RankAssociate Professor

Specialization:

  • Experimental Endocrinology

Research Interests:

  • Diabetes Research

Contact

• 2002-2007- Ph.D. degree in experimental endocrinology, Clinical Research Center, Lund university, Lund, Sweden. • The title of my thesis “Stem cell Plasticity, hype or Hope?” • 1999-2001- M.Sc. degree in biomedical laboratories, Department of infectious diseases and Medical Microbiology, Lund University, Lund, Sweden. • The title of my thesis “ Helicobacter infection” • • 1992-1997- B.Sc. degree, Medical Laboratory Technology, Al-Isra University, Amman, Jordan
• 2011 – Research scientist at Lund University Diabetes Center (LUDC), Department of diabetes and Endocrinology. • 2007-Dec/2010: Coordinator of The Human Pancreatic Islets facility at Lund University (LUDC). • 2002-2007- PhD study at Clinical Research Center, Lund University. • 2014-2016: Medical Advisor, Comoray, Lund, Sweden
Member of the editorial board of • Journal of Endocrinology and Diabetes Research • Journal of Endocrinology and Metabolism.
1- Identification of novel genes for diabetes. 2- Role of iron level in diabetes. 3- role of estrogen level in diabetes. 4. Role of vitamin A in diabetes
1. Expression Profile of SARS-CoV-2 Host Receptors in Human Pancreatic Islets Revealed Upregulation of ACE2 in Diabetic Donors. Jalal Taneera ,Waseem El-Huneidi, Mawieh Hamad, Abdul Khader Mohammed, Esraa Elaraby 1 and Mahmood Yaseen Hachim. Biology. https://doi.org/10.3390/biology9080215 2. Genetic Variants of the PLCXD3 Gene Are Associated with Risk of Metabolic Syndrome in the Emirati Population. Aljaibeji H, Mohammed AK, Alkayyali S, Hachim MY, Hasswan H, El-Huneidi W, Taneera J, Sulaiman N. Genes (Basel). 2020 Jun 18;11(6):665. doi: 10.3390/genes11060665. PMID: 32570874 Free PMC article. 3. An Integrative Phenotype-Genotype Approach Using Phenotypic Characteristics from the UAE National Diabetes Study Identifies HSD17B12 as a Candidate Gene for Obesity and Type 2 Diabetes. Hachim MY, Aljaibeji H, Hamoudi RA, Hachim IY, Elemam NM, Mohammed AK, Salehi A, Taneera J, Sulaiman N. Genes (Basel). 2020 Apr 23;11(4):461. doi: 10.3390/genes11040461. PMID: 32340285 Free PMC article. 4. Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells. Bajbouj K, Shafarin J, Taneera J, Hamad M. Biology (Basel). 2020 Apr 1;9(4):68. doi: 10.3390/biology9040068. PMID: 32244623 Free PMC article. 5. Prediabetes and diabetes prevalence and risk factors comparison between ethnic groups in the United Arab Emirates.Hamoudi R, Saheb Sharif-Askari N, Saheb Sharif-Askari F, Abusnana S, Aljaibeji H, Taneera J, Sulaiman N. Sci Rep. 2019 Nov 25;9(1):17437. doi: 10.1038/s41598-019-53505-7. 6. Potential role of hypothalamic microRNAs in regulation of FOS and FTO expression in response to hypoglycemia. Mussa BM, Taneera J, Mohammed AK, Srivastava A, Mukhopadhyay D, Sulaiman N. J Physiol Sci. 2019 Nov;69(6):981-991. doi: 10.1007/s12576-019-00718-0. Epub 2019 Nov 14. 7. Reduced expression of PLCXD3 associates with disruption of glucose sensing and insulin signalling in pancreatic β-cells. Hayat Saad Aljaibeji, Abdul Khader Mohammed, Sarah Dhaiban, Noha Mousaad Elemam, Nabil Sulaiman, Albert Salehi, Jalal Taneera. 2019. Journal. Frontiers in Endocrinology. Volume 10 Pages. 735. 8. Reduced Expression of Chl1 gene Impairs Insulin Secretion by Down-Regulating the Expression of Key Molecules of β-cell Function. Taneera J, Dhaiban S, Hachim M, Mohammed AK, Mukhopadhyay D, Bajbouj K, Hamoudi R, Salehi A, Hamad M. Exp Clin Endocrinol Diabetes. 2019 Oct 15. doi: 10.1055/a-1014-2544. [Epub ahead of print] 9. Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced β-cell dysfunction. Taneera J, Mohammed I, Mohammed AK, Hachim M, Dhaiban S, Malek A, Dunér P, Elemam NM, Sulaiman N, Hamad M, Salehi A. Mol Cell Endocrinol. 2019 Sep 21;499:110592. doi: 10.1016/j.mce.2019.110592. [Epub ahead of print] 10. GNAS gene is an important regulator of insulin secretory capacity in pancreatic β-cells. Taneera J, Dhaiban S, Mohammed AK, Mukhopadhyay D, Aljaibeji H, Sulaiman N, Fadista J, Salehi A. Gene. 2019 Oct 5;715:144028. doi: 10.1016/j.gene.2019.144028. Epub 2019 Jul 30. 11. Dimethyloxalylglycine (DMOG) and the Caspase Inhibitor "Ac-LETD-CHO" Protect Neuronal ND7/23 Cells of Gluocotoxicity. Mukhopadhyay D, Hammami M, Khalouf A, Shaikh YA, Mohammed AK, Hamad M, Salehi A, Taneera J. Exp Clin Endocrinol Diabetes. 2019 Jun 11. doi: 10.1055/a-0919-4489. 12. The Case for an Estrogen-iron Axis in Health and Disease. Hamad M, Bajbouj K, Taneera J. Exp Clin Endocrinol Diabetes. 2019 Apr 12. doi: 10.1055/a-0885-1677. 13. RORB and RORC associate with human islet dysfunction and inhibit insulin secretion in INS-1 cells.Taneera J, Mohammed AK, Dhaiban S, Hamad M, Prasad RB, Sulaiman N, Salehi A. Islets. 2019;11(1):10-20. doi: 10.1080/19382014.2019.1566684. Epub 2019 Feb 14. PMID: 30762474 14. Silencing of the FTO gene inhibits insulin secretion: An in vitro study using GRINCH cells. Taneera J, Prasad RB, Dhaiban S, Mohammed AK, Haataja L, Arvan P, Hamad M, Groop L, Wollheim CB. Mol Cell Endocrinol. 2018 Sep 5;472:10-17. doi: 10.1016/j.mce.2018.06.003. Epub 2018 Jun 8. 15. Maturity-Onset Diabetes of the Young: An Overview with Focus on the Middle East. Taneera J, Mussa B, Saber-Ayad M, Dhaiban S, Aljaibeji H, Sulaiman N. Curr Mol Med. 2017;17(8):549-562.
Master level: 1. Xhang Mi (2013-Lund University). 2. David Atac (2015-Lund University). 3. Sarah Dhaiban (2017-University of Sharjah). 4. Amina Laham (2018- University of Sharjah). 5. Nujood Alkhdran (2020-University of Sharjah). 6. Linah Alrefaei (2020-University of Sharjah). PhD level: Hayat Aljaibeji (2017-2020- University of Sharjah)
• Oral presentation award at 9th EDEC, Emirates diabetes and endocrine congress (7-9 March) 2019 Dubai-UAE. Best Young Investigator on diabetes research in Scandinavian countries, Helsinki, Finland. • New investigator award, 34th annual scientific meeting of the international society of experimental Hematology, Glasgow, UK. 2005. • Best Young Investigator on diabetes research in Scandinavian countries, 2013, Helsinki, Finland
1- member of the animal care facility at University of Sharjah 2- member of the Research committee at the college of medicine.
Teaching philosophy: I have the experience and talent to teach cell and molecular biology course. As a teacher I strive to engage, challenge, and inspire growth in my students. It is my belief that every student is capable of tasting the passion that I feel for cell biology. My first goal is to create an atmosphere that encourages participation and involvement. My teaching history is not only a practical experience, but it is a passion that I have lived, grown and adhered to. I always have the commitment not only to deliver the correct knowledge but also to use to best method to teaching students. I prefer to teach through demonstrations: by conducting experiments and analyzing data in the classroom, by participating in small group debates and role-plays, by observing and chronicling behaviors from “the real world,” and by discussing design case studies. I encourage my students to ask questions, and I am straightforward about not having all of the answers. When I become “stuck” I seek the input of my colleagues, my books, and the endless array of resources that can be found on the Internet. When I next return to the classroom, I share not only the answer that I’ve found, but also the process I went through to discover it. Above all else, I challenge my students to understand that I am open to their thoughts, eager to hear their opinions, and thrilled to learn with and through them. I believe in the essence of students involvement working in groups or on projects in most of my courses. I take seriously my responsibility to guide discussion and to explicate new or difficult material, but I do so in a manner that encourages rather than suffocates thoughtful dissent and lively questioning. Face-to face instruction has continually challenged me to make lessons fresh and effective. Teaching cell and molecular biology to students is exciting in its demands and personally rewarding. It has also improved my research and writing, as I review and present topics in different ways, with broad perspectives, and to new audiences.
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