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Goals and Objectives

Goal 1: Analyze the Influence of Exposure to Common Environmental Toxins and Risk Factors on Human Cells and Their Relation to Cancer Development at the Molecular Level.

​1.1. Characterize the specific genetic mutations and epigenetic changes induced by common environmental toxins.

1.2. Investigate the dose-response relationship between toxin exposure and molecular alterations in human cells.

1.3. Explore the temporal dynamics of toxin-induced molecular changes during cancer initiation and progression.

 

Goal 2: Dissect Signaling Pathways and Mechanisms of Disease Development with a Focus on Carcinogenesis.

2.1. Identify key oncogenic signaling pathways involved in the development of different cancer types.

2.2. Determine the crosstalk and interactions between multiple signaling pathways in carcinogenesis.

2.3. Investigate the role of genetic and epigenetic alterations in pathway dysregulation.

 

Goal 3: Analyze the Impact of Oxidative Stress and Antioxidants on Vascular Remodeling and Human Health.

3.1. Quantify oxidative stress markers in different vascular disease models and patient populations.

3.2. Assess the effects of antioxidant treatments on vascular remodeling and related health outcomes.

3.3. Investigate the role of oxidative stress in the pathogenesis of specific vascular diseases (e.g., atherosclerosis).

 

Goal 4: Explore the Effects of Nutritional Intervention, Fasting, and Dietary Chemoprevention on Health and Diseases such as Cancer.

4.1. Conduct clinical trials to evaluate the impact of specific diets on cancer prevention and treatment.

4.2. Investigate the molecular mechanisms underlying the effects of fasting on disease management.

4.3. Identify and characterize dietary components with chemopreventive and therapeutic potential.

 

Goal 5: Explore the Use of Environmental and Other Agents in Treating Cancer and Other Diseases.​

5.1. Screen a library of environmental agents for their potential as anticancer therapies.

5.2. Investigate the mechanisms of action of promising agents in cancer cell lines and animal models.

5.3. Evaluate the safety and efficacy of selected agents in preclinical and clinical trials.

 

Goal 6: Study Corrosion Prevention to Promote Environmental Factors on Human Health.

6.1. Assess the environmental and health impacts of corrosion in specific regions and industries.

6.2. Develop and implement corrosion prevention strategies in collaboration with relevant stakeholders.

6.3. Monitor and measure the health improvements resulting from reduced environmental corrosion.