The study is a collaboration between the University of Sharjah (Dr. Jalal Taneera, College of medicine) and Lund University (Dr. Albert Salehi) showed that activation of GPR183 receptor by a specific metabolite (7α, 25-dihydroxy cholesterol), which form in the liver leads to increased insulin release. That means that if you have high cholesterol then this specific metabolite is produced and the consequence is an increased insulin release, which leads to hunger, and if you eat more then you gain weight. The finding may also have another important significance as the production of insulin is also linked to increased hunger and obesity.