1. Farheen Alam, Fatima Mezhal, Hussain EL Hasasna, Vidhya A Nair, Aravind S.R., Maha Saber Ayad, Ahmed El-Serafi, Wael M Abdel-Rahman. The role of p53-microRNA 200-Moesin axis in invasion and drug resistance of breast cancer cells. Tumor Biology, accepted 2017 (in press)
2. Wael M Abdel-Rahman, Noura A. Al-khayyal, Vidhya A Nair, Aravind S.R., Maha Saber-Ayad. Role of AXL in invasion and drug resistance of colon and breast cancer cells and its association with p53 alterations. World J Gastroenterology. 2017, 23(19):3440-3448.
3. Abdel-Rahman WM, Faris ME, Peltomäki P. Molecular determinants of colon cancer susceptibility in the East and West. Curr Mol Med. 2017, 17:34-45.
4. Abdel-Rahman WM, Lotsari-Salomaa JE, Kaur S, Niskakoski A, Knuutila S, Järvinen H, Mecklin JP, Peltomäki P. The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking beta-Catenin/TCF Regulated Transcription. Gastroenterology Research and Practice. 2016 Vol 2016: 1-11 Article ID 6089658.
5. Joensuu EI, Nieminen TT, Lotsari JE, Pavicic W, Abdel-Rahman WM, Peltomäki P. Methyltransferase expression and tumor suppressor gene methylation in sporadic and familial colorectal cancer. Genes Chromosomes Cancer. 2015 Dec;54(12):776-87.
6. Nieminen TT, O'Donohue MF, Wu Y, Lohi H, Scherer SW, Paterson AD, Ellonen P, Abdel-Rahman WM, Valo S, Mecklin JP, Järvinen HJ, Gleizes PE, Peltomäki P. Germline Mutation of RPS20, Encoding a Ribosomal Protein, Causes Predisposition to Hereditary Nonpolyposis Colorectal Carcinoma Without DNA Mismatch Repair Deficiency. Gastroenterology 2014 Sep;147(3):595-598.e5.
7. Abdel-Rahman WM, Nieminen TT, Shoman S, Eissa S, Peltomäki P. Loss of p15INK4b Expression in Colorectal Cancer is Linked to Ethnic Origin. Asian Pacific Journal for Cancer Prevention. 2014;15(5):2083-2087.
8. Abdel-Rahman WM, Moustafa YM, Ahmed BO, Mostafa RM. Endocrine disruptors and breast cancer risk – time to consider the environment. Asian Pacific Journal for Cancer Prevention. 2012 13(12) 5937-5946
9. Saleh EM, El-Awady RA, Eissa NA, Abdel-Rahman WM. Antagonism between curcumin and the topoisomerase II inhibitor etoposide: A study of DNA damage, cell cycle regulation and death pathways. Cancer Biol Ther. 2012 Sept; 13(11):1058-1071.
10. Abdel-Rahman W M, Ruosaari S, Knuutila S, P Peltomäki. Differential roles of EPS8 in carcinogenesis: Loss of protein expression in a subset of colorectal carcinoma and adenoma. World Journal of Gastroenterology. 2012 Aug 7;18(29):3896-903.
11. Lotsari JE, Gylling A, Abdel-Rahman WM, Nieminen TT, Aittomäki K, Friman M, Pitkänen R, Aarnio M, Järvinen HJ, Mecklin JP, Kuopio T, Peltomäki P. Breast carcinoma and Lynch syndrome: molecular analysis of tumors arising in mutation carriers, non-carriers, and sporadic cases. Breast Cancer Res. 2012 Jun 12;14(3):R90.
12. Carlsson E, Ranki A, Sipilä L, Karenko L, Abdel-Rahman WM, Ovaska K, Siggberg L, Aapola U, Assämäki R, Häyry V, Niiranen K, Helle M, Knuutila S, Hautaniemi S, Peltomäki P, Krohn K. Potential role of a navigator gene NAV3 in colorectal cancer. Br J Cancer. 2012 Jan 31;106(3):517-24.
13. Nieminen TT, Shoman S, Eissa S, Peltomäki P, Abdel-Rahman WM. Distinct Genetic and Epigenetic Signatures of Colorectal Cancers According to Ethnic Origin. Cancer Epidemiol Biomarkers Prev. 2012 Jan;21(1):202-11.
14. Nieminen TT, Abdel-Rahman WM, Ristimaki A, Lappalinen M, Lahermo P, Mecklin JP, Järvinen HJ, Peltomäki P. BMPR1A mutatins in herditary nopolyposis colorectal cancer without mismatch repair deficiency. Gastroenterology, 2011 Jul;141(1):e23-6.
15. Nieminen TT, Gylling A, Abdel-Rahman WM, Nuorva K, Aarnio M, Renkonen-SinisaloL, Järvinen HJ, Mecklin JP, Bützow R, Peltomäki P. Molecular analysis of endometrial tumorigenesis: importance of complex hyperplasia regardless of atypia. Clin Cancer Res. 2009;15(18):5772-83.
16. Abdel-Rahman WM. Genomic instability and carcinogenesis: an update. Current Genomics 2008, 9:535-541
17. Abdel-Rahman WM, Peltomäki P. Lynch syndrome and related familial colorectal cancers. Crit Rev Oncog. 2008;14(1):1-22
18. Joensuu EI, Abdel-Rahman WM, Ollikainen M, Ruosaari S, Knuutila S, Peltomäki P., Epigenetic signatures of familial cancer are characteristic of tumor type and family category. Cancer Research 2008 Jun 15;68(12):4597-605.
19. Gylling AH, Nieminen TT, Abdel-Rahman WM, Nuorva K, Juhola M, Joensuu EI, Järvinen HJ, Mecklin JP, Aarnio M, Peltomäki PT. Differential cancer predisposition in Lynch syndrome: insights from molecular analysis of brain and urinary tract tumors. Carcinogenesis. 2008 Jul;29(7):1351-9.
20. Hahtola S, Burghart E, Jeskanen L, Karenko L, Abdel-Rahman WM, Polzer B, Kajanti M, Peltomäki P, Pettersson T, Klein CA, Ranki A. Clinicopathological characterization and genomic aberrations in subcutaneous panniculitis-like T-cell lymphoma. J Invest Dermatol. 2008 Sep;128(9):2304-9.
21. Abdel-Rahman WM, Kalinina J, Shoman S, Eissa S,Ollikainen M, Elomaa O, Eliseenkova A, Bützow R, Mohammadi M, Peltomäki P. Somatic mutations of FGF9 in colorectal and endometrial carcinomas,(2008) Human Mutation, 29(3):390-397.
22. Abdel-Rahman WM, Peltomäki P, Knuutila S, Harrison DJ, Bader SA. Truncation of MBD4 predisposes to reciprocal chromosomal translocations and alters the response to therapeutic agents. (2008) DNA Repair 7:321-328.
23. Hahtola S, Burghart E, Puputti M, Karenko L, Abdel-Rahman WM, Väkevä L, Jeskanen L, Virolainen S, Karvonen´J, Salmenkivi K, Kinnula V, Joensuu H, Peltomäki P, Klein C, Ranki AM. Cutaneous T-cell lymphoma-associated lung cancer show chromosomal abberations differing from primary lung cancer. (2008) Genes Chromsomes and Cancer, 47:107-117.
24. Ollikainen M, Gylling A, Nupponen N, Abdel-Rahman WM, Butzow R, Peltomäki P. Patterns of PIK3CA alterations in familial colorectal and endometrial carcinoma. (2007), International Journal of Cancer. 121(4):915-920.
25. Gylling A, Abdel-Rahman WM, Juhola M, Nuorva K, Hautala E, Jarvinen HJ, Mecklin JP, Aarnio M, Peltomaki P. (2007). Is gastric cancer part of the tumor spectrum of hereditary nonpolyposis colorectal cancer? - A molecular genetic study.Gut. 56(7):926-933
26. Ollikainen M, Hannelius U, Lindgren CM, Abdel-Rahman WM, Kere J, Peltomaki P. Mechanisms of inactivation of MLH1 in hereditary nonpolyposis colorectal carcinoma: a novel approach. Oncogene. 2007 26(31):4541-4549.
27. Abdel-Rahman WM. Mutations of β-catenin and KRAS in colorectal carcinomas. Digestive Diseases and Sciences (2006) 51(3):616-617.
28. Abdel-Rahman WM, Mecklin JP., Peltomäki P. (2006) The genetics of HNPCC: application to diagnosis and screening. Critical Reviews in Oncology/Haematology 58:208-220
29. Renkonen E, Nieminen P, Abdel-Rahman WM, Moisio A-L, Järvela I, Arte S, Järvinen HJ, Peltomäki P. Adenomatous polyposis families that screen APC mutation negative are genetically heterogenous. Journal of Clinical Oncology 2005;23(24):5651-9.
30. Ollikainen M, Abdel-Rahman WM, Moisio A-L, Lindroos A, Kariola R, Jarvela I, Poyhonen M, Butzow R, Peltomäki P. (2005) Molecular analysis of familial endometrial carcinoma: a manifestation of hereditary non-polyposis colorectal cancer or a separate syndrome. Journal of Clinical Oncology 23(21):4609-4616.
31. Kariola R, Abdel-Rahman WM (equal contribution), Ollikainen M, Butzow R, Nyström M, Peltomäki P. (2005) APC and beta-catenin protein expression patterns in HNPCC- related endometrial and colorectal cancers. Familial Cancer 4(2):187-90.
32. Abdel-Rahman W M. (2005) Multiple reciprocal translocations in carcinomas. Cancer Genetics & Cytogenetics, 158:194-195.
33. Abdel-Rahman WM, Ollikainen M, Kariola R, Järvinen H, Mecklin J-P, Nyström-Lahti M, Knuutila S, Peltomäki P. (2005) Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations. Oncogene, 24:1542-1551.
34. Abdel-Rahman WM, Lohi H., Knuutila S., and Peltomäki P. (2005) Restoring mismatch repair does not stop the formation of reciprocal translocations in the colon cancer cell line HCA7 but further destabilizes chromosome number. Oncogene 24:706-713.
35. Abdel-Rahman WM and Peltomäki P. (2004) Molecular basis and diagnostics of hereditary colorectal cancers. Annals of Medicine, 36: 379-388
36. Raevaara TE, Gerdes AM, Lonnqvist KE, Tybjaerg-Hansen A, Abdel-Rahman WM, Kariola R, Peltomäki P, and Nyström-Lahti M. (2004) HNPCC mutation MLHI P648S makes the functional protein unstable, and homozygosity predisposes to mild neurofibromatosis type 1. Genes Chromosomes & Cancer, 40: 261-265.
37. Renkonen E, Zhang Y, Lohi H, Salovaara R, Abdel-Rahman WM, Nilbert M, Aittomäki K, Järvinen HJ, Mecklin J-P, Lindblom A, Peltomäki P. (2003) Altered expression of MLH1, MSH2 and MSH6 in predisposition to hereditary nonpolyposis colorectal cancer. Journal of Clinical Oncology 21:3629-37.
38. Raevaara TE, Vaccaro C, Abdel-Rahman WM, Mocetti E, Bala S, Lönnqvist KE, Kariola R, Lynch HT, Peltomäki P, Nyström-Lahti M (2003) Pathogenicity of the hereditary colorectal cancer mutation hMLH1 del616 linked to shortage of the functional protein. Gastroenterology 125:501-509.
39. Abdel-Rahman WM, Katsura K, Rens W, Gorman PA, Sheer D, Bicknell D, Bodmer WF, Arends MJ, Wyllie AH, Edwards PAW (2001). Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement. Proceedings of the National Academy of Sciences USA 98: 2538-2543.
40. Abdel-Rahman WM, Georgiades IB, Curtis LJ, Arends MJ and Wyllie AH. (1999). Role of BAX mutations in mismatch repair-deficient colorectal carcinogenesis. Oncogene 18:2139-2142.
41. Abdel-Rahman WM, Arends MJ, Morris RG, Ramadan ME, Wyllie AH. (1999). Death pathway genes Fas (Apo-1/CD95) and Bik (nbk) show no mutations in colorectal carcinomas. Cell Death and Differentiation 6:387-388