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المنشورات

2020

  1. Ahmad F, Woodgett JR. Emerging roles of GSK-3α in pathophysiology: Emphasis on cardio-metabolic disorders. Biochim Biophys Acta Mol Cell Res. 2020;1867(2):118616.  
  2. Ahmad F, Tomar D, Aryal A C S, Elmoselhi AB, Thomas M, Elrod JW, Tilley DG, Force T. Nicotinamide riboside kinase-2 alleviates ischemia-induced heart failure through P38 signaling. Biochim Biophys Acta Mol Basis Dis. 2020; 1866(3):165609
  3. Erlotinib can halt adenine induced nephrotoxicity in mice through modulating ERK1/2, STAT3, p53 and apoptotic pathways. Ahmed M. Awad, Mohamed A. Saleh, Nashwa M. Abu-Elsaad, Tarek M. Ibrahim. Scientific Reports. July, 2020; 10 (11524).
  4. Highly-reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension Joseph K. Prinsen, Prince J. Kannankeril, Tatiana N. Sidorova, Liudmila V. Yermalitskaya, Olivier Boutaud, Joey V. Barnett, Matthew B. Murphy, Tuerdi Subati, Joshua M. Stark, Isis Christopher, Scott R. Jafarian-Kerman, Mohamed A. Saleh, Allison E. Norlander, Roxana Loperena, James M. Luther, Venkataraman Amarnath, Sean S. Davies, Annet Kirabo, Meena S. Madhur, David G. Harrison, and Katherine T. Murray. Journal of the American College of Cardiology (JACC): Basic to Translational Science. 2020 June; 5(6): 602-615.
  5. The Rationale for Potential Pharmacotherapy of COVID-19. Maha Saber-Ayad, Mohamed A. Saleh, Eman Abu-Gharbieh. Pharmaceuticals. 2020 May 14;13(5):E96.
  6. Brown, J.L.; Lawrence, M.M.; Ahn, B.; Kneis, P.; Piekarz, K.M.; Qaisar, R.; Ranjit, R.; Bian, J.; Pharaoh, G.; Brown, C., et al. Cancer cachexia in a mouse model of oxidative stress. J Cachexia Sarcopenia Muscle 2020, 10.1002/jcsm.12615, doi:10.1002/jcsm.12615.
  7. Bhaskaran, S.; Pollock, N.; P, C.M.; Ahn, B.; Piekarz, K.M.; Staunton, C.A.; Brown, J.L.; Qaisar, R.; Vasilaki, A.; Richardson, A., et al. Neuron-specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice. Aging Cell 2020, 10.1111/acel.13225, e13225, doi:10.1111/acel.13225.
  8. Qaisar, R.; Karim, A.; Muhammad, T. Plasma CAF22 Levels as a Useful Predictor of Muscle Health in Patients with Chronic Obstructive Pulmonary Disease. Biology (Basel) 2020, 9, doi:10.3390/biology9070166.
  9. Karim, A.; Qaisar, R. Anthropometric measurements of school-going-girls of the Punjab, Pakistan. BMC Pediatr 2020, 20, 223, doi:10.1186/s12887-020-02135-4.
  10. Qaisar, R.; Karim, A.; Muhammad, T. Circulating Biomarkers of Handgrip Strength and Lung Function in Chronic Obstructive Pulmonary Disease. Int J Chron Obstruct Pulmon Dis 2020, 15, 311-321, doi:10.2147/COPD.S225765.
  11. Qaisar, R.; Karim, A.; Elmoselhi, A.B. Muscle unloading: A comparison between spaceflight and ground-based models. Acta Physiol (Oxf) 2020, 228, e13431, doi:10.1111/apha.13431.
  12. Bajbouj K, Ramakrishnan RK, Saber-Ayad M, Omar HA, Sharif-Askari NS,, Elmoselhi A, Ihmaid A, Ali SAH, Alalool A, Abdullah R, Hamid Q, Protein arginine methyltransferase-5  Selective Inhibitor Enhances Therapeutic Effects of Cisplatin on Lung Cancer Cells. BMC Cancer 2020: in press
  13. Wafaa S Ramadan; Dana M Zaher; Alaa M Altaie; Iman Mamdouh Talaat, Adel Elmoselhi. Potential Therapeutic Strategies for Lung and Breast Cancers Through Understanding the Anti-angiogenesis Resistance Mechanisms.  International Journal of Molecular Sciences Int. J. Mol. Sci. 2020, 21, 565.

 

2019

  1. Kannan M, Ahmad F, Saxena R. Platelet activation markers in evaluation of thrombotic risk factors in various clinical settings. Blood Reviews 2019 Sept;37:100583.
  2. Ahmad F, Singh AP, Tomar D, Rahmani M, Zhang Q, Woodgett JR, Tilley DG, Lal H, Force T. Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overload. J Mol Cell Cardiol. 2019 Mar 27;130:65-75.
  3. Ahmad F, Kannan M, Obser T, Budde U, Schneppenheim S, Saxena R, Schneppenheim R. Characterization of VWF gene conversions causing von Willebrand disease. Br J Haematol. 2019 Mar;184(5):817-825.
  4. Qaisar, R.; Bhaskaran, S.; Ranjit, R.; Sataranatarajan, K.; Premkumar, P.; Huseman, K.; Van Remmen, H. Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weakness. Redox Biol 2019, 20, 68-74, doi:10.1016/j.redox.2018.09.018.
  5. Abedalqader F, Alhuarrat M, Altamimi A, Ibrahim G. Shukur M, Taha F, Elmoselhi AB: The Correlation between Smart Device Usage & Sleep Quality among UAE Residents. Sleep Medicine, 2019; 63: 18-23.

 

2018

  1. Ahmad F. Vaccination: a novel potential therapeutic approach to limit thrombosis. J Am Heart Assoc. 2018 Jun 23;7(13). pii: e009861
  2. Gupte M, Tumuluru S, Sui J, Singh AP, Umbarkar P, Parikh S, Ahmad F, Zhang Q, Force T, Hind Lal. Cardiomyocyte-Specific Deletion of GSK-3β Leads to Cardiac Dysfunction in a Diet Induced Obesity Model. Int J Cardiol. 2018: 259;145–152.
  3. Joshua A. Keefe, Shih-Jen Hwang, Tianxiao Huan, Michael Mendelson, Chen Yao, Paul Courchesne, Mohamed A. Saleh, Meena S. Madhur and Daniel Levy. Evidence for a Causal Role of the SH2B3-β2M Axis in Blood Pressure Regulation. Hypertension. 2018;73:497–503.
  4. Fanny Laroumanie, Arina Korneva, Matthew R Bersi, Matthew Alexander, Liang Xiao  Xue Zhong, Justin P Van Beusecum, Yuhan Chen, Mohamed A. Saleh, William McMaster, Kyle A. Gavulic,  Bethany L. Dale, Shilin Zhao ,Yan Guo ,Yu Shy, Daniel S. Perrien, Nancy Cox, John Curci, Jay D. Humphrey and Meena S. Madhur. LNK Deficiency Promotes Acute Aortic Dissection and Rupture. The Journal of Clinical Investigation – Insight. 2018;3(20):e122558.
  5. Qaisar, R.; Bhaskaran, S.; Premkumar, P.; Ranjit, R.; Natarajan, K.S.; Ahn, B.; Riddle, K.; Claflin, D.R.; Richardson, A.; Brooks, S.V., et al. Oxidative stress-induced dysregulation of excitation-contraction coupling contributes to muscle weakness. J Cachexia Sarcopenia Muscle 20189, 1003-1017.
  6. M. Bakri Alaa, Yazan Ghazi Al Shaikh, Anas Mohammad Hashem, Obaida M. Mukhles Adi, Ihab Aal-yaseen , Ziad Mahmoud El Menawy, Adel B. Elmoselhi: Knowledge, attitudes and practices towards caffeine consumption among adults in the United Arab Emirates. Journal of Caffeine and Adenosine Research,2018;8:2

 

2017

  1. Gupte M, Lal H Ahmad F, Sawyer DB, Hill MF. Chronic Neuregulin-1Β Treatment Mitigates the Progression of Post-Myocardial Infarction Heart Failure in the Setting of Type 1 Diabetes Mellitus by Suppressing Myocardial Apoptosis, Fibrosis and Key Oxidant-Producing Enzymes. J Card Fail. 2017: S1071-9164(17)31159-4.
  2. Mohammed Soutto*, Mohamed A. Saleh*, M. Simo Arredouani, Blanca Piazuelo, Abbes Belkhiri, Wael El-Rifai. Loss of Tff1 promotes pro-inflammatory phenotype with increase in the levels of RORγt+ T lymphocytes and IL-17 in mouse gastric neoplasia (* equal contribution). Journal of Cancer 2017; 8(13):2424-2435.
  3. Allison E. Norlander, Mohamed A. Saleh, Arvind K. Pandey, Hana A. Itani, Jing Wu, Liang Xiao, Jooeun Kang, Bethany L. Dale, Slavina B. Goleva, Fanny Laroumanie, Liping Du, David G. Harrison, Meena S. Madhur. A Salt Sensing Kinase in T Lymphocytes, SGK1, Drives Hypertension and Hypertensive End-Organ Damage. The Journal of Clinical Investigation – Insight. 2017 Jul 6;2(13).
  4. Fanny Laroumanie, Bethany L. Dale, Mohamed A. Saleh and Meena S. Madhur. Intracellular Staining and Flow Cytometry to Identify Lymphocyte Subsets within Murine Aorta, Kidney and Lymph Nodes in a Model of Hypertension. J Vis Exp. 2017 Jan 28;(119). doi: 10.3791/55266.
  5. Bhaskaran, S.; Unnikrishnan, A.; Ranjit, R.; Qaisar, R.; Pharaoh, G.; Matyi, S.; Kinter, M.; Deepa, S.S. A fish oil diet induces mitochondrial uncoupling and mitochondrial unfolded protein response in epididymal white adipose tissue of mice. Free Radic Biol Med 2017108, 704-714, doi:10.1016/j.freeradbiomed.2017.04.028.
  6. Adel Elmoselhi, Editor and Author (2017). Cardiology: An Integrated Approach. McGraw-Hill Education / Medical https://accessmedicine.mhmedical.com/book.aspx?bookID=2224

 

2016

  1. Zhou J*, Ahmad F*, Lal H, Force T. Response by Zhou et al to Letter Regarding Article, "Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy". Invited commentary Circ Res. 2016;119:e29-e30 *Equal first author
  2. Zhou J*, Ahmad F*, Parikh S, Hoffman NE, Rajan S, Verma VK, Song J, Yuan A, Shanmughapriya S, Guo Y, Gao E, Koch W, Woodgett JR, Madesh M, Kishore R, Lal H, Force T. Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy. Circ Res 2016: 118;1208-1222. *Equal first author
  3. Mohamed A. Saleh, David I. Stevens, Carmen De Miguel, Pamela K. Carmines, David M. Pollock and Jennifer S. Pollock. Free radical scavenging decreases endothelin-1 excretion and glomerular albumin permeability during type 1 diabetes. Physiological Reports 2016 Dec;4(24).
  4. Mohamed A. Saleh, Allison E. Norlander and Meena S. Madhur. Inhibition of Interleukin-17A, But Not Interleukin-17F, Signaling Lowers Blood Pressure, and Reduces End-Organ Inflammation in Angiotensin II–Induced Hypertension. Journal of the American College of Cardiology (JACC): Basic to Translational Science. 2016 Dec;1(7):606-616.
  5. Lehanna N. Sanders, John A. Schoenhard, Mohamed A. Saleh, Amrita Mukherjee, Sergey Rhyzov, William G. McMaster Jr., Kristof Nolan, Richard J. Gumina, Thomas B. Thompson, David G. Harrison and Antonis K. Hatzopoulos. The BMP signaling antagonist Grem2 limits inflammation after myocardial infarction. Circulation Research. 2016 Jul 22;119(3):434-449.
  6. Hana A. Itani, William G. McMaster Jr, Mohamed A. Saleh, Rafal R. Nazarewicz, Tomasz P. Mikolajczyk, Anna Kaszuba, Anna Konior, Aleksander Prejbisz, Andrzej Januszewicz, Allison E. Norlander, Wei Chen, Rachel H. Bonami, Andrew F. Marshall, Greg Poffenberger, Cornelia M. Weyand, Meena S. Madhur, Daniel J. Moore, David G. Harrison, Tomasz J. Guzik. Activation of human T cells in angiotensin II-induced hypertension: Studies of humanized mice. Hypertension. 2016 Jul ;68:123-132.
  7. Allison E. Norlander, Mohamed A. Saleh, Nikhil V. Kamat, Benjamin Ko, Juan Gnecco, Linjue Zhu, Bethany Dale, Yoichiro Iwakura, Robert S. Hoover, Alicia McDonough, Meena S. Madhur. Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II–Induced Hypertension. Hypertension. 2016 Jul ;68:167-174.
  8. Hana A. Itani, Liang Xiao, Mohamed A. Saleh, Jing Wu, Mark A. Pilkinton, Bethany L. Dale, Natalia R. Barbaro, Jason D. Foss, Annet Kirabo, Kim R. Montaniel, Allison E. Norlander, Wei Chen, Ryosuke Sato, L. Gabriel Navar, Simon A. Mallal, Meena S. Madhur, Kenneth E. Bernstein, and David G. Harrison. CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive Stimuli. Circulation Research 2016 Apr 15; 118(8): 1233–1243.
  9. Jing Wu, Mohamed A. Saleh, Annet Kirabo, Hana Itani, Liang Xiao, Wei Chen, Raymond Mernaugh, Hua Cai, Kenneth E. Bernstein, Jörg J. Goronzy, Cornelia M. Weyand, Sean Davies, L. Jackson Roberts II, Meena Madhur, David G. Harrison. Immune activation caused by vascular oxidation promotes fibrosis and hypertension. The Journal of Clinical Investigation 2016 Jan;126(1):50-67.
  10. Daniel S. Perrien, Mohamed A. Saleh, Keiko Takahashi, Meena S. Madhur, David G. Harrison, Raymond C. Harris, and Takamune Takahashi. Novel Methods for microCT-Based Analyses of Vasculature in the Renal Cortex Reveal a Loss of Arterioles and Perfusable Glomeruli in eNOS−/− Mice. BMC Nephrology 2016 Mar 2;17(1):24.
  11. Jing Wu, Kim Montaniel, Mohamed A. Saleh, Liang Xiao, Wei Chen, Gary Owens, Jay Humphrey, Mark Majesky, Antonis Hatzopoulos, Meena S Madhur, and David G. Harrison. The Origin of Matrix-Producing Cells that Contribute to Aortic Fibrosis in Hypertension. Hypertension 2016 Feb;67(2):461-8.
  12. Gurley, J.M.; Ilkayeva, O.; Jackson, R.M.; Griesel, B.A.; White, P.; Matsuzaki, S.; Qaisar, R.; Van Remmen, H.; Humphries, K.M.; Newgard, C.B., et al. Enhanced GLUT4-Dependent Glucose Transport Relieves Nutrient Stress in Obese Mice Through Changes in Lipid and Amino Acid Metabolism. Diabetes 2016, 65, 3585-3597, doi:10.2337/db16-0709.
  13. Qaisar, R.; Bhaskaran, S.; Van Remmen, H. Muscle fiber type diversification during exercise and regeneration. Free Radic Biol Med 2016, 98, 56-67, doi:10.1016/j.freeradbiomed.2016.03.025.
  14. Deepa, S.S.; Bhaskaran, S.; Ranjit, R.; Qaisar, R.; Nair, B.C.; Liu, Y.; Walsh, M.E.; Fok, W.C.; Van Remmen, H. Down-regulation of the mitochondrial matrix peptidase ClpP in muscle cells causes mitochondrial dysfunction and decreases cell proliferation. Free Radic Biol Med 2016, 91, 281-292, doi:10.1016/j.freeradbiomed.2015.12.021.

 

2015

  1. Lal H, Ahmad FWoodgett JR, Force T. The GSK-3 family as a therapeutic target for myocardial diseases. Circ Res. 2015 Jan 2;116(1):138-149.
  2. Walsh, M.E.; Bhattacharya, A.; Sataranatarajan, K.; Qaisar, R.; Sloane, L.; Rahman, M.M.; Kinter, M.; Van Remmen, H. The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging. Aging Cell 2015, 14, 957-970, doi:10.1111/acel.12387.
  3. Sataranatarajan, K.; Qaisar, R.; Davis, C.; Sakellariou, G.K.; Vasilaki, A.; Zhang, Y.; Liu, Y.; Bhaskaran, S.; McArdle, A.; Jackson, M., et al. Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype. Redox Biol 2015, 5, 140-148, doi:10.1016/j.redox.2015.04.005.
  4. Minetto, M.A.; Qaisar, R.; Agoni, V.; Motta, G.; Longa, E.; Miotti, D.; Pellegrino, M.A.; Bottinelli, R. Quantitative and qualitative adaptations of muscle fibers to glucocorticoids. Muscle Nerve 2015, 52, 631-639, doi:10.1002/mus.24572.