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Prof. Mawieh Hamad Faculty Member, Dept of Medical Lab Sciences Academic RankProfessor

Specialization:

  • Molecular Immunology

Research Interests:

  • Hormonal regulation of iron metabolism in cancer and immunity

Contact

o B.Sc., Biological Sciences, 1990, Oklahoma State University, Stillwater, OK, USA o Ph.D., Molecular Immunology, 1995, University of Tulsa, Tulsa, OK, USA. Title of PhD Dissertation: Characterization of the extrathymic pathway of murine intestinal intraepithelial lymphocyte (i-IEL) development
• Professor and Chair, Department of Medical Laboratory Sciences, University of Sharjah, UAE, Jan. 2016-Present. • Associate Professor and Chair, Department of Medical Laboratory Sciences, University of Sharjah, UAE, Sep. 2014-Jan. 2016. • Associate Professor, Department of Medical Laboratory Sciences, University of Sharjah, UAE, Sep. 2011-Present. • Technical Consultant (QC/QA and R&D Departments), JMS Medicals, Toronto, Canada / Zarqa, Jordan, Dec. 2008-Dec. 2011. • Associate Professor, Taif University School of Medicine, Taif, KSA, Sept. 2006-Sept. 2008. • Associate Professor, Department of Biology & Biotechnology, Faculty of Science, Hashemite University, Jordan, Aug. 2003-Sept. 2006. • Assistant Professor, Department of Biology & Biotechnology, Faculty of Science, Hashemite University, Jordan, Sept. 1999-Aug. 2003.
• Faculty Member at the department of Medical Laboratory Sciences, UOS • Chair of the department of Medical Laboratory Sciences, UOS • Research group leader at the Sharjah Institute for Medical Research, UOS
• Canadian Society for Immunology, Canada. • Middle East Molecular Biology Society, Dubai, UAE. • National Center for Biotechnology (NCB), Higher Council for Science and Technology (HCST), Amman, Jordan.
• University of Sharjah collaborative research grant. Evaluating the capacity of estrogen-mediated downregulation of hepcidin synthesis to deplete intracellular iron stores in breast cancer cells. Principal Investigator. • University of Sharjah Research Group Grant. (2016-2017) Iron Biology Group. Group Leader. • Evaluating the anti-carcinogenic potential of biologically-driven intracellular iron depletion. 2016 (2 years). Al-Jalila Foundation.
• Hamad M. S. Awadallah. 2013. Estrogen-dependent changes in serum iron levels as a translator of the adverse effects of estrogen during infection: a conceptual framework. Medical Hypothesis; 81(6):1130-4. http://dx.doi.org/10.1016/j.mehy. • Hamad M. 2014. Estrogen treatment predisposes to severe and persistent vaginal candidiasis in diabetic mice. Journal of Diabetes and Metabolic Disorders; 13:15. (in press); DOI: 10.1186/2251-6581-13-15. • Kausik Datta, Hamad M. 2015. Immunotherapy of human fungal infections. Invited review, Journal of Immunological investigations, 2015; 44(8): 738–776. • Shafarin J, K. Bajbouj, A. El-Serafy, D. Sandeep, M Hamad. 2016. Estrogen-dependent downregulation of hepcidin synthesis induces intracellular iron efflux in cancer cells in vitro. Biol Med 2016, 8:7. • Hamad M, Bajbouj K. 2016. The re-emerging role of iron in infection and immunity. Integr Mol Med, 3(5): 807-810. DOI: 10.15761/IMM.1000251
Theses and Projects Supervision: • Mohammed M. Ghaleb, MSc student, Department of Biology, Hashemite University. Title of Thesis: Characterization and phenotypic profiling of T cell subsets residing within the vaginal mucosa of Candida albicans-infected mice. • Mohammed Al-Janaydeh, MSc student, Department of Biology, Hashemite University. Title of Proposal: Allelic frequency distribution and normal values of haptoglobin in Jordanian Blacks. • Hamza Abu Sheikaha, MSc student, Department of Biology, Hashemite University. Title of Thesis: Assessment of the relationship between Hp polymorphism and serum antioxidant status in patients with chronic renal failure. • Rula K. Y. Harierah, MSc student, Department of Biology, Hashemite University. Title of Thesis: Hematological and biochemical parameters in estrogen-treated C. albicans-infected mice. Co-advisor: • Enas El-Younis, MSc student, Department of Biology, Hashemite University. Title of Thesis: Clonotypic analysis of vaginal T lymphocytes during experimental estrogen-induced vaginal candidosis in the murine system. • Ameera Al-Sadeq, MSc student, Department of Biology, Hashemite University. Title of Thesis: Phenotypic characterization of vaginal T lymphocyte activation markers during experimental vaginal candidiasis in mice. Co-advisor: • Nesreen Al-Khofash, MSc student, Molecular Medicine program, College of medicine, UOS, Jan. 2017-present
Teaching Philosophy: Textbooks, lecture notes, and exams are all useful and should always be part of undergraduate teaching. However, biomedical students can greatly benefit from hands-on experience in collecting, analyzing, and interpreting information. Problem solving exercises, case scenarios, discussion groups, class presentations, mini lab projects and experiments as well as field trips are activities that stimulate the curios and inquisitive minds of undergraduate students. This teaching model entails a shift in the role of the instructor; in that, besides weekly lecturing sessions, the instructor is given a greater chance at constantly challenging his/her students to think and improvise and be inventive and creative. He/she is also given a greater chance at directing student learning activities, guiding students through their weekly workloads, and evaluating their progress by multiple means. Successful implementation of modern teaching tools and aids (the blackboard model for example) to help in disseminating information, instructor/student communication, student evaluation, and student record documentation is wholly dependent upon adopting this learning paradigm.
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