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Master in Pharmaceutical Sciences

College
College of Pharmacy
Department
Pharmacy
Tracks
Pharmacology Pharmaceutics Medicinal Chemistry
Commenced Year
2018
Location
Sharjah Main Campus
Level
Masters
Study System
Thesis
Total Credit Hours
33 Cr. Hrs
Fees
Total 100.485 AED
Duration
2-4 Years
Language
English
Intake
Fall & Spring
Study Mode
Full Time and Part Time

Master in Pharmaceutical Sciences

Introduction
Pharmacy is becoming a key player in primary and preventive health care and is defined as the science of the composition, use and dispensing of drugs. The study and practice of Pharmacy has evolved and expanded considerably over the years due to the exponential growth of the health care and pharmaceutical industry.

The College of Pharmacy (CoP) was established in 2004, seven years after the foundation of University of Sharjah (UoS). The first batch of the college students was awarded the Bachelor of Pharmacy (B. Pharm.) degree at the end of the academic year of 2008/2009. Since its foundation, the CoP is continuously updating its curriculum, to keep pace with the rapidly evolving pharmacy profession. Considering the facts related to, shortage in the qualified pharmaceutical scientists worldwide (2, 3), to keep up with the developments of various pharmacy fields in the UAE and across the Gulf region, and to answer the repeated pharmacy inquiries from our college and the colleges of pharmacy graduates across the UAE regarding postgraduate programs, CoP proposes a program of MASTER OF PHARMACEUTICAL SCIENCES.

The academic aim of the program is to prepare students for professional roles in the area of pharmacy, with the knowledge and skills to advance the discipline from the academic, research and practical standpoints. The M. Pharm. Sci. program will prepare the students to address the current and future challenges in disciplines such as patient care, pharmaceutical industry, health promotion, research and development, management and investment in drug industry, and academic positions. The intent is also to prepare students to engage in independent and collaborative research in academic, governmental and applied life science contexts. During this educative process, students will participate in knowledge generation and improvement, research synthesis, and knowledge/technology transfer.

There are only two Master in pharmaceutical sciences programs offered in the UAE, the existence of CoP within the medical campus of the UoS and having the Sharjah Institute of Medical Research inside this campus will make the program highly attractive for pharmacy graduates looking for graduate programs.

Program Objectives
Program Goals

  1. Provide students with advanced knowledge and experimental techniques in research in the field of pharmaceutical sciences.
  2. Train students and enhance their ability to analyze and interpret data, design and conduct research in their field of expertise and apply analytical and critical thinking in reviewing literature.
  3. Develop students' ability to effectively communicate scientific information both orally and in writing to scientists and non-scientists.
  4. Provide a challenging and innovative learning environment so as to prepare the students for further advanced graduate or professional programs or scientific careers in the pharmaceutical industries.
  5. Develop the students' ability to engage in life-long learning and exhibit professionalism with the highest ethical standards.
  6. Foster problem-solving and decision-making skills applied to facilitate employment in scientific careers that contributes to the growth and development of the society.

Program Structure & Requirements
The College of Pharmacy only offers programs on the University of Sharjah main campus. The proposed M. Pharm program will be offered on the main campus of the University of Sharjah.

Program Concentrations
The proposed master program is thesis-dependent program, which includes both courses and thesis.

After the initial general study during the first semester, students select one of three concentrations:
1.   Pharmacology
2.   Pharmaceutics
3.   Medicinal Chemistry

Program Structure
Components Credit hours
General Courses 12
Concentration-specific Courses 12
M. Pharm Thesis 9
Total 33
 

The completion of 33 credits is required for the program. The course work includes 12 credit hours of general compulsory courses, 12 credit hours of specialized courses, and a 9 credit hours for the master thesis.

 
Special Admission Requirements
To check admission requirements, Click Here !

  

Course Description

General Courses

1103613 Experimental Design and Data Analysis (2-0:2)
The course will cover single factor experiments, multiple factors, full factorial and fractional factorial designs and screening designs, the fundamentals of hypothesis testing and relevant biostatistics. ​ ​
 

1103611 Research Ethics (3-0:3)
The course will cover single factor experiments, multiple factors, full factorial and fractional factorial designs and screening designs, the fundamentals of hypothesis testing and relevant biostatistics. ​ ​
 

1102612
Pharmaceutical Sciences Journal Club-I    (1-0:1)
This course is designed to enhance the ability of graduate students to critically evaluate peer-reviewed scientific articles. Articles will be selected from current scientific literature in a variety of disciplines in pharmaceutical sciences, including drug delivery, drug development, medicinal chemistry, pharmacology, and pharmaceutics. Each student will present 2-4 articles per semester. The articles are selected by a supervisor guided student. ​ ​
 

1103612
Research Seminar (1-0:1)
This course introduces students to the academic research process and exposes students to strategies of problem-solving. It trains students on critical thinking, research, writing, and documentation. During the course, students will be assigned to come up with a research proposal including a key scientific question and they will conduct research into the literature related to their scientific question and they should develop a research design that addresses this question and provide more knowledge to this field. Students will give a presentation about a certain topic followed by a discussion in which all students are evaluated based on participation. Students are given a short essay assignment based on each presentation. The student presentations and short essays count toward the final grade. A research paper also is assigned. ​ ​
 

1102615 Pharmaceutical Sciences Journal Club-II    (1-0:1)
This course is designed to enhance the ability of graduate students to critically evaluate peer-reviewed scientific articles. Articles will be selected from current scientific literature in a variety of disciplines in pharmaceutical sciences, including drug delivery, drug development, medicinal chemistry, pharmacology, and pharmaceutics. Each student will present 2-4 articles per semester. The articles are selected by a supervisor guided student. ​ ​
 

1101611 Instrumental Analysis (3-0:3)
This course will introduce the MS. students with the basic instrumental techniques including infrared, UV-Vis, nuclear magnetic resonance spectroscopy (1 & 2D NMR techniques), mass spectrometry and different chromatographic techniques, used for qualitative and quantitative analysis of organic compounds, the course will also include practical applications through qualitative and quantitative analysis of unknown samples (single and mixture of components) using spectroscopic and chromatographic techniques. ​ ​
 

1102611 Foundation of Pharmaceutical Sciences (3-0:3)
The purpose of this course is for students to practice application of their knowledge in basic pharmaceutical sciences to a variety of conditions and states of health and disease.  In this course, students are trained to use basic pharmacokinetic and pharmacodynamics principles in optimizing therapeutic outcomes in variety of disorders. Principles in formulation of biotechnological products and engineering delivery systems for biotechnology products, lipid based, polymer based and physical delivery approaches. Also included in the course are applied pharmacokinetics principles in developing an appropriate therapeutic regimen in renal and cardiovascular disorders. Protein structure, stability, structure prediction methods, protein drug discovery and protein engineering. ​ ​
 

Medicinal Chemistry

1101612
Advanced Organic Chemistry (3-0:3)
The course will cover single factor experiments, multiple factors, full factorial and fractional factorial designs and screening designs, the fundamentals of hypothesis testing and relevant biostatistics. ​ ​
 

1101621 Advanced Pharmaceutical Analysis (3-0:3)
This course will focus on pharmaceutical and biopharmaceutical analysis, Topics to be studied includes, control of the quality of the analytical method, physical and chemical properties of drug molecules, development and validation of analytical methods of pharmaceutical and biopharmaceutical according to the ICH and FDA, sample preparation and extraction of pharmaceuticals and bio-pharmaceuticals, the course will also include qualitative and quantitative methods of analysis of drug molecules and related substances  in raw material, finished products and biological matrix using stability indicating methods ( HPLC, GC, LC/MS and GC/MS), enantio-selective separation, in  addition good analytical practice [GAP] and good laboratory practice [GLP] will be discussed. ​ ​
 

1101622
Advanced Topics in Medicinal Chemistry (3-0:3)
This course surveys the strategies and techniques used to transform biologically active molecules into potential therapeutic agents. Forward and reverse chemical genetics approaches will be discussed. Diversity-oriented synthesis; fragment-based as well as rational- and structure-based drug design will be discussed. Further topics include: sources of molecular leads, qualitative and quantitative structure-activity relationship analysis, improving pharmacokinetics and reducing toxicity based on functional groups/isosteres modifications. A flavor of an introduction to bioorganic chemistry will be included in the course. The course concludes with case histories of successful drug discovery illustrating the application of design principles taught in the class. ​ ​
 

1101631
Special Topics in Medicinal Chemistry (3-0:3)
This course will explore some important topics in medicinal chemistry research. For example, Medicinal chemistry of cancer therapeutics, e.g. epigenetics proteins as drug targets, kinases, cancer stem-cells drug targets. Medicinal chemistry of CNS and inflammatory diseases drug targets. Recent advances in antiviral drugs. The course is designed to integrate the information from drug targets, molecular mechanism of action, organic synthesis and drug resistance for pharmacists. The course emphasizes on the drugs that are being clinically used and potential new drug targets. ​ ​
 

1101632
Advanced Pharmaceutical Analysis 1 (3-0:3)
This course will focus on drug stability studies( real time and accelerated stabilities testing), statistics and data processing, It will also emphasize on  spectroscopic  analysis  including Atomic Absorption Spectroscopy (AAS), Atomic Emission Spectroscopy AES & Flame Photometry and Inductively coupled plasma-atomic emission spectroscopy & ICP-AES and their applications in pharmaceutical analysis, it will also include  the  pharmacopoeial method of analysis concerning raw material and all pharmaceutical dosage forms.
​ ​
 

Pharmaceutics

1103623
Regulatory Affairs (3-0:3)
This course will cover fundamentals and concepts of regulation of pharmaceuticals prevailing in different countries.  The course will focus on the regulatory strategies and market authorization approvals from different countries. Regulations for non-clinical studies, clinical trials, submission and review, and good manufacture practice (GMP) will be discussed. ​ ​
 

1103621
Advanced Drug Delivery Systems (3-0:3)
This course will introduce students to a variety of recent topics in the area of controlled drug delivery and relevant biomedical applications. Each topic will provide a comprehensive and critical examination of current and emerging research on the design and development of advanced drug delivery systems and their applications to experimental and clinical therapeutics. Emphasis is given to polymer based systems and assembled Nano-carriers and scaffolds for the delivery of therapeutic drugs, proteins, vaccines and genes. ​ ​
 

1103622 Advanced Pharmaceutics (3-0:3)
This course covers advanced topics in physical pharmacy and biopharmaceutics including the influence of physico-chemical properties of drugs and biological factors on drug delivery and design of dosage forms. The course will discuss the principles and concepts of drug selection, drug absorption and transport through various systems, drug metabolism, drug delivery design with special emphasis on targeted drug delivery. ​ ​
 

1103614 Advanced Pharmacy Management (3-0:3)
The course provides an overview on community/retail pharmacy setting where students learn the various aspects involved with managing a pharmacy.  The primary focus is financial analysis including third-party issues, budgeting, control, and personnel management as well as financial risk management. ​ ​
 

1103615
Advanced Cosmetics & Parapharmaceuticals (3-0:3)
This course discusses the principles applied in the formulation design of cosmetics and parapharmaceuticals.  The course will devote focus to the use of nanostructured delivery systems in skin care products. Dispersed systems used in delivery of active compounds to the skin such as microemulsions, nanoemulsions, multiple emulsions and lipid/polymer based delivery systems will be discussed. Safety assessment and regulations governing cosmetics will also be discussed. ​ ​
 

Pharmacology

1102613
Molecular Pharmacology    (3-0:3)
This course comprises the detailed principles of molecular pharmacology including receptors and cell signaling. As examples, the course focuses on the mechanism of action of anti-microbial agents, anti-neoplastic agents, anti-arrhythmic agents, anti-psychotic agents and anti-diabetic agents. The course discusses the principles of pharmaco-genetics/-genomics and its role in drug development. ​ ​
 

1102622 Pharmacogenomics (3-0:3)
· This course will give students a broad perspective on the critical role played by genetics in drug therapy and the emergence of pharmacogenomics as a new field.
· It will provide an insight into the growing importance of this field and the prospective role it will play in clinical therapeutics and future drug design.
· Topics to be studied include common methodologies used in the application of pharmacogenomics, the role pharmacogenomics in altering drug pharmacokinetics and pharmacodynamics, the role of pharmacogenomics in the pharmacotherapy of various diseases of the cardiovascular, CNS, hematologic, respiratory and immune systems as well as cancer and toxico-genomics. ​ ​
 

1102621
Gene and Stem Cells Therapy (3-0:3)
This course will focus on gene therapy and stem cells as major approaches to treat inherited human diseases and cancer. It will cover the general principles and basic mechanisms in gene therapy. It will also illustrate the compilations of current clinical trial efforts, methods of gene delivery, immune therapeutics, oncolytic virus therapeutics, antisense therapeutics as well as ethical considerations. ​ ​
 

1102623 Neuropharmacology (3-0:3)
The neuropharmacology course will discuss the various central neurotransmitters, their pathways and drug-induced changes in functioning of the nervous system. The specific focus of this course will be to provide a description of the cellular and molecular actions of drugs on synaptic transmission. This course will also refer to specific diseases of the nervous system including drug dependence and their treatment in addition to giving an overview of the techniques used for the study of neuropharmacology. ​
 

1102624 Principles of Cancer Chemotherapy  (3-0:3)
This course will focus on the role of drugs in management of cancer.  Topics to be studied include the relationship between cancer biology and the response of cancer cells to treatment with anti-cancer agents with emphasize on cell signaling, DNA damage induction and repair, cell cycle regulation and apoptosis. Classification of anti-cancer drugs, their mode of action, adverse effects, mechanisms of resistance and ways to overcome it will also be studied. ​ ​
 

Thesis

1105635 Research thesis-I (3-0 :3)
Student will produce and defend a thesis under the supervision of a faculty member in one of the three concentrations offered. This course integrates different skills including hypothesis formulation, research techniques, review of literature, proposal and thesis writing, and oral presentation and discussion. Student (in collaboration with the supervisor) will propose a research point that would be implemented through laboratory work, survey analysis or any other tool. Student will present the results of each stage in a seminar within the department. After completion of the research work, student will prepare a thesis including all his/her work and will defend the research work in front of a discussion committee who will approve/disapprove the research thesis. ​ ​
 

(6-0:6) Research thesis-II 1105636
Student will produce and defend a thesis under the supervision of a faculty member in one of the three concentrations offered. This course integrates different skills including hypothesis formulation, research techniques, review of literature, proposal and thesis writing, and oral presentation and discussion. Student (in collaboration with the supervisor) will propose a research point that would be implemented through laboratory work, survey analysis or any other tool. Student will present the results of each stage in a seminar within the department. After completion of the research work, student will prepare a thesis including all his/her work and will defend the research work in front of a discussion committee who will approve/disapprove the research thesis. ​ ​