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Overview and Goals
The human body is susceptible to infections by many pathogens. Pathogens can include bacteria, viruses, parasites and fungi. Diseases such as malaria, measles, leprosy, hepatitis and tuberculosis, and more recent infections due to HIV, EBOLA, Zika, and dengue fever are posing serious threat to mankind with unacceptable mortality and morbidity. Infectious diseases not only cause illness and death, but also can disrupt the socioeconomic progress of countries. Infectious diseases continue to be among the most serious public health problems around the world and may include UAE because of (i) There is no updated surveillance systems maintained in large parts of the world in particular the developing countries, (ii) International travel and migration in particular in the Gulf region, and (iii) Numerous outbreaks of drug- resistant microbes were documented around the world.

As a research group, our major objectives can be specified into
  1. Accurate epidemiological and statistical analysis: This will provide support to national and local capabilities to improve the process of detection and the analysis of changes in the frequency and distribution of common, newly emerging and re-emerging infectious diseases and to implement proper prevention and control activities.

  2. Investigation of pathogenesis mechanisms: To accurately investigate and discover new pathogenesis and resistance mechanisms used by the pathogens in particular those mediated with virulent factors and toxins and to evaluate the changes in the immunity/ inflammatory responses in the patient as a result of infections.

  3. Treatment: To develop and discover effective antimicrobials including chemical therapeutics (natural or synthetic) and/ or antibodies and vaccines to target specific virulence factors that enables the microbe to become pathogenic. In addition, we aim to identify optimal antimicrobial dosing protocols in order to achieve precise and targeted therapy.   

  4. Diagnosis: To develop cost-effective measures to prevent and control infectious diseases, to be used as future diagnostic kits.