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Publications
Significant Research publications

(TOTAL 42, IMPACT POINTS 310, TOTAL CITATIONS 1047, H-INDEX 19)

1.Joensuu EI, Nieminen TT, Lotsari JE, Pavicic W, Abdel-Rahman WM, Peltomäki P. Methyltransferase expression and tumor suppressor gene methylation in sporadic and familial colorectal cancer. Genes Chromosomes Cancer. 2015 Aug 25. doi: 10.1002/gcc.22289. [Epub ahead of print] PubMed PMID: 26305882.

2.Taina T Nieminen, Marie-Françoise O'Donohue, Yunpeng Wu, Hannes Lohi, Stephen W Scherer, Andrew D Paterson, Pekka Ellonen, Wael M Abdel-Rahman, Satu Valo, Jukka-Pekka Mecklin, Heikki J Järvinen, Pierre-Emmanuel Gleizes, Päivi Peltomäki.  Germline Mutation of RPS20, Encoding a Ribosomal Protein, Causes Predisposition to Hereditary Nonpolyposis Colorectal Carcinoma Without DNA Mismatch Repair Deficiency. Gastroenterology 2014 Sep;147(3):595-598.e5.

3.Abdel-Rahman WM, Nieminen TT, Shoman S, Eissa S, Peltomäki P.  Loss of p15INK4b Expression in Colorectal Cancer is Linked to Ethnic Origin. Asian Pacific Journal for Cancer Prevention. 2014;15(5):2083-2087.

4.Abdel-Rahman WM, Moustafa YM, Ahmed BO, Mostafa RM. Endocrine disruptors and breast cancer risk – time to consider the environment. Asian Pacific Journal for Cancer Prevention. 2012 13(12) 5937-5946

5.Saleh EM, El-Awady RA, Eissa NA, Abdel-Rahman WM.  Antagonism between curcumin and the topoisomerase II inhibitor etoposide: A study of DNA damage, cell cycle regulation and death pathways. Cancer Biol Ther. 2012 Sept; 13(11):1058-1071.

6.Abdel-Rahman W M, Ruosaari S, Knuutila S, P Peltomäki.  Differential roles of EPS8 in carcinogenesis: Loss of protein expression in a subset of colorectal carcinoma and adenoma. World Journal of Gastroenterology. 2012 Aug 7;18(29):3896-903.

7.Lotsari JE, Gylling A, Abdel-Rahman WM, Nieminen TT, Aittomäki K, Friman M, Pitkänen R, Aarnio M, Järvinen HJ, Mecklin JP, Kuopio T, Peltomäki P. Breast carcinoma and Lynch syndrome: molecular analysis of tumors arising in mutation carriers, non-carriers, and sporadic cases. Breast Cancer Res. 2012 Jun 12;14(3):R90.

8.Carlsson E, Ranki A, Sipilä L, Karenko L, Abdel-Rahman WM, Ovaska K, Siggberg L, Aapola U, Assämäki R, Häyry V, Niiranen K, Helle M, Knuutila S, Hautaniemi S, Peltomäki P, Krohn K. Potential role of a navigator gene NAV3 in colorectal cancer. Br J Cancer. 2012 Jan 31;106(3):517-24.

9.Nieminen TT, Shoman S, Eissa S, Peltomäki P, Abdel-Rahman WM. Distinct Genetic and Epigenetic Signatures of Colorectal Cancers According to Ethnic Origin. Cancer Epidemiol Biomarkers Prev. 2012 Jan;21(1):202-11.

10.Nieminen TT, Abdel-Rahman WM, Ristimaki A, Lappalinen M, Lahermo P, Mecklin JP, Järvinen HJ, Peltomäki P. BMPR1A mutatins in herditary nopolyposis colorectal cancer without mismatch repair deficiency. Gastroenterology, 2011 Jul;141(1):e23-6.

11.Joensuu EI, Abdel-Rahman WM, et al. Epigenetic signatures of familial cancer are characteristic of tumor type and family category. Cancer Research 2008 Jun 15;68(12):4597-605.

12.Abdel-Rahman WM, et al. Somatic mutations of FGF9 in colorectal and endometrial carcinomas,(2008) Human Mutation, 29(3):390-397.

13.  Abdel-Rahman WM, et al. Truncation of MBD4 predisposes to reciprocal chromosomal translocations and alters the response to therapeutic agents. (2008)  DNA Repair 7:321-328.

14.Abdel-Rahman WM, Ollikainen M, Kariola R, Järvinen H, Mecklin J-P, Nyström-Lahti M, Knuutila S, Peltomäki P. (2005) Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations. Oncogene, 24:1542-1551.

15.Abdel-Rahman WM, ......, Wyllie AH, Edwards PAW (2001).  Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement. Proceedings of the National Academy of Sciences USA 98: 2538-2543.

16.Abdel-Rahman WM, Georgiades IB, Curtis LJ, Arends MJ and Wyllie AH. (1999). Role of BAX mutations in mismatch repair-deficient colorectal carcinogenesis. Oncogene 18:2139-2142.



2- - Name:Professor Randa M.Mostafa

Contact detail:mostafaranda@sharjah.ac.ae

 Office : 7204

Cellular : 00971(50)8014065                

Awards/Grants •            

 2011: Excellency in University and community service Award , University of sharjah , UAE.

2009 : Excellency in Research Award , University of sharjah , UAE.