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  • Post Graduate Students Thesis Defense Day

  1. Raafat A. El-Awady, Mohammad H. Semreen, Maha M. Saber, Farhan Cyprian, Varsha Menon, Taleb H. Al-Tel. Modulation of DNA damage response and induction of apoptosis mediates synergism between doxorubicin and a new imidazopyridine derivative in breast and lung cancer cells. DNA repair 2015 (accepted). DOI:10.1016/j.dnarep.2015.10.004
  2. El-Awady RA, Herzi F, Al-Tunaiji H, Saleh EM, Abdel-Wahab AH, Al Homssi A, Suhail M, El-Serafi A, Al-Tel T.Epigenetics and miRNA as predictive markers and targets for lung cancer chemotherapy. Cancer Biol Ther. 2015, 16(7): 1056 - 1070
  3. Semreen MH, El-Awady R, Abu-Odeh R, Saber M, Al-Qawasmeh RA, Chouaib S, Al-Tel TH, Voelter W. Tandem Multicomponent Reactions Toward the Design and Synthesis of Novel Antibacterial and Cytotoxic Motifs. Curr Med Chem. 2013;20(11):1445-59.
  4. M. T. Ardah, K. E. Paleologou, u. Lv, S. B. Abul Khair, A. S. Kazim, S. T. Minhas, Taleb H. Al-Tel, A. Al-Hayani, M. E. Haque, D. Eliezer and O. M. A. El-Agnaf; "Structure activity relationship of phenolic acid inhibitors of α-synuclein fibril formation and toxicity"; Front. Aging Neurosci., 05 August 2014 | doi: 10.3389/fnagi.2014.00197.
  5. A. El-Dahshan, S. I. Al-Gharabli, S. Radetzki, Taleb H. Al-Tel, P. Kumar, J. Rademann; "Flexible, polymer-supported synthesis of sphingosine derivatives provides ceramides with enhanced biological activity",  Bioorganic & Medicinal Chemistry, July 2014 DOI: 10.1016/j.bmc.2014.07.024.

  6. Al-Tel TH, Semreen MH, Al-Qawasmeh RA, Schmidt MF, El-Awadi R, Ardah M, Zaarour R, Rao SN, El-Agnaf O. Design, Synthesis, and Qualitative Structure-Activity Evaluations of Novel β-Secretase Inhibitors as Potential Alzheimer's Drug Leads.J Med Chem. 2011 Dec 22;54(24):8373-85. Epub 2011 Nov 16.
  7. Abdel-Nasser El-Shorbagi, Hamadeh Tarazi, Mohammad Semreen, Alaa Hayallah. Targeting some THTT derivatives as scaffold for dopamine to CNS, neuroprotective agents, computation and docking on GSK-3β. International Journal of Pharma Sciences and Research,2014, 5, 8, 460-469.
  8. Subash Chandra Sahoo, Naba K. Nath, Lidong Zhang, Mohammad H. Semreen, Taleb H. Al-Tel and Panče Naumov, Actuation based on thermo/photosalient effect: a biogenic smart hybrid driven by light and heat, RSC Adv., 2014,4, 7640-7647.
  9. Raed A. Al-Qawasmeh, Monther A. Khanfar, Mohamad H. Semreen, Raed Abu Odeh, and Taleb H. Al-Tel, Design and synthesis of new hybrid triazine-indol derivatives as potential antimicrobial agents against hospital resistant strains, Heterocycles, 2013, 87, 11, 2385-2394.
  10. Hany A. Omar, Wafaa R. Mohamed, El-Shaimaa A. Arafa, Basim A. Shehata, Gamal A. El Sherbiny, Hany H. Arab, Abdel Nasser. A. M. Elgendy. Hesperidin alleviates cisplatin-induced hepatotoxicity in rats without inhibiting its antitumor activity. Pharmacological Reports, September 2015.  10.1016/j.pharep.2015.09.007 
  11. Jui-Hsiang Hung, Chia-Yun Chen, Hany A. Omar, Kuo-Yuan Huang, Che-Chia Tsao, Chien-Chih, Chiu, Yi-Ling Chen, Po-Han Chen, Yen-Ni Teng. Reactive oxygen species mediate terbufos-induced apoptosis in mouse testicular cell lines via the modulation of cell cycle and pro-apoptotic proteins. Environmental Toxicology, September 2015  DOI: 10.1002/tox.22190
  12. Kuan-Han Lee, Hany A. Omar, Shu-Jing Wu, Pin-Shern Chen, Yu-Chung Chen, Yen-Ni Teng, Hung-Chang Huang, Clay C. C. Wang and Jui-Hsiang Hung. The effect of reactive oxygen species produced by 6-shogaol on cell cycle progression and cell death-associated signaling pathways in human hepatoma cells. European Journal of Pharmacology, June 2015, 762(5) 449–458.
  13. Ahmed H. Abdelazeem, Ahmed M. Gouda, Hany A. Omar, Mai F. Tolba. Design, Synthesis and Biological Evaluation of Novel Diphenylthiazole-Based Cyclooxygenase Inhibitors as Potential Anticancer Agents. Bioorganic Chemistry, Dec 2014, 57, 132–141.
  14. Hany A. Omar, Mai F. Tolba and Maha M. Saber-Ayad. Potential Targets of Energy Restriction Mimetic Agents in Cancer Cells. Future Oncology, 2014 Dec;10(16): 2547-2550.
  15. Hany A. Omar, El-Shaimaa A. Arafa, A. Maghrabi and Jing-Ru Weng. Sensitization of Hepatocellular Carcinoma Cells to Apo2L/TRAIL by a Novel Akt/NF-kB Signaling Inhibitor. Basic & Clinical Pharmacology & Toxicology, 2014 Jun;114(6):464-71. 
  16. Kuan-Han Lee, Wen-Yueh Ho, Shu-Jing Wu, Hany A. Omar, Po-Jui Huang, Clay C. C. Wang and Jui-Hsiang Hung. Modulation of cyclins, p53 and MAPK signaling in breast cancer cell lines by 4-(3,4,5-trimethoxyphenoxy)benzoic acid. International Journal of Molecular Sciences, 2014, 15(1), 743-757. 
  17. El-Shaimaa A. Arafa, Ahmed H. Abdelazeem, Hany H. Arab and Hany A. Omar. OSU-CG5, a Novel Energy Restriction Mimetic Agent Inhibits Colorectal Cancer Cells. Acta Pharmacologica Sinica,   2014 Mar; 35(3):394-400.