7 October 2018
An interdisciplinary collaborative project grant entitled "Stimulus-Responsive Nanoparticles for Intraoperative NIR Imaging and Treatment of Pancreatic Cancer" was awarded funding from the Engineering and Physical Sciences Research Council (EPSRC) in United Kingdom.
The project is interdisciplinary and spans the area of bioengineering and medical health interface. The aim of the project is to exploit using nanotechnology and the use of Indocyanine green (ICG) for developing a system that has significant potential to increase the efficacy of surgical treatment in pancreatic cancer.
The aspect of intraoperative treatment can also reduce the need for extensive post-operative radiotherapy and exposure to ionizing radiation. The proposed theranostic system has the potential to be adopted for the combined near infra-red guided surgical resection and intraoperative treatment of different cancers.
The work will be a collaboration between Dr. Nikolitsa Nomikou (EPSRC PI) and Professor Alexander MacRobert at the Division of Surgery and Interventional Science, University College London, United Kingdom who will lead on the nanotechnology and energy based therapy aspects of the project, Professors Anthony McHale and John Callan from Northern Ireland ، who will lead on the animal models and chemistry aspects and Dr. Rifat Hamoudi at the College of Medicine/ Research Institute of Medical and Health Sciences at the University of Sharjah, United Arab Emirates who will lead on the design, implementation, bioinformatics and the molecular characterization of the impact of ICG nanoparticles on pancreatic tumor and microenvironment cells.