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Pharmacology Labs - IA 

 

Pharmacology Labs [Pharmacology - IA]

Introduction

Pharmacology of drugs, their mechanisms of action; therapeutic uses, adverse effects and drug interaction are covered in theoretical classes. However, to appreciate such principles and the importance of testing drugs for their effects, practical classes aim to illustrate such effects on isolated and whole animal preparations. In this laboratory classes, we will introduce students to handle animals and learn them pharmacokinetic principles also students will investigate some of the responses of guinea pig ileum preparation to several drugs, ranging from dose–response studies to demonstration of selective antagonism. Also they will learn about effects of drugs on Rabbits eye to understand autonomic pharmacology. The sympathetic and parasympathetic control of pupil diameter and how pupil diameter changes in response to a change in ambient light intensity will be extensively covered.

Equipment and Instruments

  • Water still W4000
  • Electronic Balances
  • Thermostatic bath
  • Microscope
  • Oven UNB
  • UV Lamp Bench Type
  • pH Meter
  • Animal Temperature Recorder
  • Rat Restrainer Adjustable Length
  • Rabbit Restrainer Adjustable Length
  • UV – Visible Spectrophotometer
  • Precision Triple Beam Balance
  • Cary Eclipse Florescence
  • Spectrophotometer with Computer
  • Centrifuges
  • Refrigerator
  • Chest Freeze
  • Silent Crusher (Homogenizer)
  • Bone Cutter-Nickel Plated Carbon Steel
  • Dissecting Set
  • HARVARD Stimulator
  • Harvard Apparatus Oscillographs
  • Small Animal Ventilator
  • VERSAMAX Analyzer
  • Thermo Circulator
  • Single Heated Tissue Bath
  • Hot Plates
  • Operator Table for Animal
  • Isometric & Isotonic Transducers
  • Blood Pressure Transducer
  • Endotracheal Tube Set
  • Friedman Bone Rongeurs Curved
  • Omron Blood Pressure Monitor
  • ABE Refractometer Manual
  • Vortex Mixer
  • Melting Point Apparatus
  • Homoeothermic Control Units for Medium & Small Animals
  • Mettle Toddler Microbalance
  • Hot Plate Analgesia Meter Harvard
  • PC Cardiogram with Computer
  • Sterotaxic Frame
  • Branson Ultrasonic
  • UV Cabinet with Lamp
  • Hot Bead Sterilizer for Small Surgical Instruments
  • Rotary Evaporator
  • Visiprep SPE Vacuum Manifold with Minipump
  • Animal Activity Monitor + Acer Monitor + Computer set
  • Phrenic Nerve Electrode
  • Rat, Mice & Rabbits Cages
  • Blood Pressure Monitor Mercury

Experiments

  • Experimental Animals and their Methods of Handling
  • Routes of Drug Administration & Dose Calculation
  • Drug – Drug Interactions and Drug Excretion
  • Identification of Unknown Drug
  • The Effect of Autonomic Drugs on Rabbit’s Eye
  • Guinea Pig Ileum Preparation