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Medicinal Chemistry IIB 

 

medicinal Chemistry IIB

Introduction

The practical part of this course deals with experiments on the synthesis of pharmaceutical organic compounds and detection of their purity, stability and biological activity. Experiments to study the chemical and pharmaceutical properties of pharmaceutical drugs are also included in this course in addition to the application of molecular modeling to study the three-dimensional structures of drugs and their structure activity relationship (SAR).

Equipment and Instruments

  • Analytical Balances
  • Top loading Balances
  • Hot Plates and Stirrer
  • Oven
  • Water Bath
  • Thermometer
  • Centrifuge
  • GC/MS
  • GC/FID
  • Vaccum Pump
  • UV-Vis Spectrophotometer
  • Polarimeter
  • Ice Flaking Machine
  • Reflux Apparatuse
  • Melting Point Apparatuse
  • Separator Funnel
  • Rotatory Evaporator
  • UV Cabinate
  • Thin Layer Chromotography Tanks

Experiments

  • Synthesis of Sulfasalazine
  • Determination of the Free Salicylic Acid Concentration in Aspirn... by Forming Fe+3 Complexes.
  • Synthesis of Propranolol
  • Synthesis and Chemical Analysis of Penicillins
  • Determination of Oil/Water Partition Coefficient of Mandelic Acid
  • Isolation and Identification of DNA from Yeast
  • Structural Data: The Bases for Molecular Modeling

Tests and Services

  • To Have Preliminary Idea About the Active Ingredients and Their Concentration in the Drug Dosage Forms
  • Toxic Elements Detection and Measurement in Food, Water, Soil and Other Specimens (With the Help of ICP)